TY - JOUR
T1 - BioNanotechnology and BioMEMS (BNM)
T2 - State-of-the-Art Applications, Opportunities, and Challenges
AU - Borenstein , Jeffrey
AU - Cummins, Gerard
AU - Dutta, Abishek
AU - Hamad, Eyad
AU - Hughes, Michael
AU - JIang, Xinyu
AU - Lee, Hyowon
AU - Lei, Kin Fong
AU - Tang, Shirley
AU - Chen, Jie
PY - 2023/12/7
Y1 - 2023/12/7
N2 - The development of micro- and nanotechnology for biomedical applications has defined the cutting edge of medical technology for over three decades, as advancements in fabrication technology developed originally in the semiconductor industry have been applied to solving ever-more complex problems in medicine and biology. These technologies are ideally suited to interfacing with life sciences, since they are on the scale lengths as cells (microns) and biomacromolecules (nanometers). In this paper we review the state of the art in bionanotechnology and bioMEMS (collectively BNM), including developments and challenges in the areas of BNM, such as microfluidic organ-on-chip devices, oral drug delivery, emerging technologies for managing infectious diseases, 3D printed microfluidic devices, AC electrokinetics, flexible MEMS devices, implantable microdevices, paper-based microfluidic platforms for cellular analysis, and wearable sensors for point-of-care testing.
AB - The development of micro- and nanotechnology for biomedical applications has defined the cutting edge of medical technology for over three decades, as advancements in fabrication technology developed originally in the semiconductor industry have been applied to solving ever-more complex problems in medicine and biology. These technologies are ideally suited to interfacing with life sciences, since they are on the scale lengths as cells (microns) and biomacromolecules (nanometers). In this paper we review the state of the art in bionanotechnology and bioMEMS (collectively BNM), including developments and challenges in the areas of BNM, such as microfluidic organ-on-chip devices, oral drug delivery, emerging technologies for managing infectious diseases, 3D printed microfluidic devices, AC electrokinetics, flexible MEMS devices, implantable microdevices, paper-based microfluidic platforms for cellular analysis, and wearable sensors for point-of-care testing.
U2 - 10.1039/D3LC00296A
DO - 10.1039/D3LC00296A
M3 - Review article
SN - 1473-0197
VL - 2023
SP - 4928
EP - 4949
JO - Lab on a Chip
JF - Lab on a Chip
IS - 23
ER -
