Abstract
Chiral nucleophilic catalysts, 6-aryl-phenyl-dihydroimidazoquinolines (PIQs), were designed, synthesised and applied to the kinetic resolution of arylalkyl carbinols with very high selectivity (S) factors (up to 530). Density functional theory calculations indicate that multiple noncovalent interactions play a key role in chiral recognition between 6-aryl-PIQ catalysts and chiral secondary alcohol substrates.
Original language | English |
---|---|
Pages (from-to) | 1909-1913 |
Number of pages | 5 |
Journal | Catalysis Science and Technology |
Volume | 4 |
Issue number | 7 |
DOIs | |
Publication status | Published - 1 Jan 2014 |
ASJC Scopus subject areas
- Catalysis