Bi-aryl rotation in phenyl-dihydroimidazoquinoline catalysts for kinetic resolution of arylalkyl carbinols

Zheng Wang; Jinjin Ye; Rui Wu; Yang Zi Liu; John S. Fossey; Jiagao Cheng; Wei Ping Deng

doi:10.1039/c3cy00904a

Bi-aryl rotation in phenyl-dihydroimidazoquinoline catalysts for kinetic resolution of arylalkyl carbinols

Zheng Wang, Jinjin Ye, Rui Wu, Yang Zi Liu, John S. Fossey, Jiagao Cheng^*, Wei Ping Deng

^*Corresponding author for this work

Chemistry

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

Abstract

Chiral nucleophilic catalysts, 6-aryl-phenyl-dihydroimidazoquinolines (PIQs), were designed, synthesised and applied to the kinetic resolution of arylalkyl carbinols with very high selectivity (S) factors (up to 530). Density functional theory calculations indicate that multiple noncovalent interactions play a key role in chiral recognition between 6-aryl-PIQ catalysts and chiral secondary alcohol substrates.

Original language	English
Pages (from-to)	1909-1913
Number of pages	5
Journal	Catalysis Science and Technology
Volume	4
Issue number	7
DOIs	https://doi.org/10.1039/c3cy00904a
Publication status	Published - 1 Jan 2014

ASJC Scopus subject areas

Catalysis

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abstract = "Chiral nucleophilic catalysts, 6-aryl-phenyl-dihydroimidazoquinolines (PIQs), were designed, synthesised and applied to the kinetic resolution of arylalkyl carbinols with very high selectivity (S) factors (up to 530). Density functional theory calculations indicate that multiple noncovalent interactions play a key role in chiral recognition between 6-aryl-PIQ catalysts and chiral secondary alcohol substrates.",

author = "Zheng Wang and Jinjin Ye and Rui Wu and Liu, {Yang Zi} and Fossey, {John S.} and Jiagao Cheng and Deng, {Wei Ping}",

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T1 - Bi-aryl rotation in phenyl-dihydroimidazoquinoline catalysts for kinetic resolution of arylalkyl carbinols

AU - Wang, Zheng

AU - Ye, Jinjin

AU - Wu, Rui

AU - Liu, Yang Zi

AU - Fossey, John S.

AU - Cheng, Jiagao

AU - Deng, Wei Ping

PY - 2014/1/1

Y1 - 2014/1/1

N2 - Chiral nucleophilic catalysts, 6-aryl-phenyl-dihydroimidazoquinolines (PIQs), were designed, synthesised and applied to the kinetic resolution of arylalkyl carbinols with very high selectivity (S) factors (up to 530). Density functional theory calculations indicate that multiple noncovalent interactions play a key role in chiral recognition between 6-aryl-PIQ catalysts and chiral secondary alcohol substrates.

AB - Chiral nucleophilic catalysts, 6-aryl-phenyl-dihydroimidazoquinolines (PIQs), were designed, synthesised and applied to the kinetic resolution of arylalkyl carbinols with very high selectivity (S) factors (up to 530). Density functional theory calculations indicate that multiple noncovalent interactions play a key role in chiral recognition between 6-aryl-PIQ catalysts and chiral secondary alcohol substrates.

UR - http://www.scopus.com/inward/record.url?scp=84902187884&partnerID=8YFLogxK

U2 - 10.1039/c3cy00904a

DO - 10.1039/c3cy00904a

M3 - Article

AN - SCOPUS:84902187884

SN - 2044-4753

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EP - 1913

JO - Catalysis Science and Technology

JF - Catalysis Science and Technology

IS - 7

ER -

Bi-aryl rotation in phenyl-dihydroimidazoquinoline catalysts for kinetic resolution of arylalkyl carbinols

Abstract

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