Base and solvent dependency of an oxidative retro-alkylation of secondary and tertiary benzylamines

A. Feula; J.S. Fossey

doi:10.1039/c3ra40228b

Base and solvent dependency of an oxidative retro-alkylation of secondary and tertiary benzylamines

A. Feula
, J.S. Fossey

Chemistry

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

An iodine and caesium carbonate amine oxidation protocol is described. Non-branched secondary benzylamines were cleanly oxidised to aldimines that could be isolated without the need for chromatography. A tertiary amine bearing an ethyl group was oxidatively de-ethylated by iodine and caesium carbonate in a DMSO-water solvent system.

Original language	English
Pages (from-to)	5370-5373
Number of pages	4
Journal	RSC Advances
Volume	3
Issue number	16
DOIs	https://doi.org/10.1039/c3ra40228b
Publication status	Published - 28 Apr 2013

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abstract = "An iodine and caesium carbonate amine oxidation protocol is described. Non-branched secondary benzylamines were cleanly oxidised to aldimines that could be isolated without the need for chromatography. A tertiary amine bearing an ethyl group was oxidatively de-ethylated by iodine and caesium carbonate in a DMSO-water solvent system.",

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AU - Fossey, J.S.

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AB - An iodine and caesium carbonate amine oxidation protocol is described. Non-branched secondary benzylamines were cleanly oxidised to aldimines that could be isolated without the need for chromatography. A tertiary amine bearing an ethyl group was oxidatively de-ethylated by iodine and caesium carbonate in a DMSO-water solvent system.

UR - https://www.scopus.com/pages/publications/84878074508

U2 - 10.1039/c3ra40228b

DO - 10.1039/c3ra40228b

M3 - Article

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SP - 5370

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JO - RSC Advances

JF - RSC Advances

IS - 16

ER -

Base and solvent dependency of an oxidative retro-alkylation of secondary and tertiary benzylamines

Abstract

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