Base and solvent dependency of an oxidative retro-alkylation of secondary and tertiary benzylamines

A. Feula; J.S. Fossey

doi:10.1039/c3ra40228b

Base and solvent dependency of an oxidative retro-alkylation of secondary and tertiary benzylamines

A. Feula, J.S. Fossey

Chemistry

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

An iodine and caesium carbonate amine oxidation protocol is described. Non-branched secondary benzylamines were cleanly oxidised to aldimines that could be isolated without the need for chromatography. A tertiary amine bearing an ethyl group was oxidatively de-ethylated by iodine and caesium carbonate in a DMSO-water solvent system.

Original language	English
Pages (from-to)	5370-5373
Number of pages	4
Journal	RSC Advances
Volume	3
Issue number	16
DOIs	https://doi.org/10.1039/c3ra40228b
Publication status	Published - 28 Apr 2013

Access to Document

10.1039/c3ra40228b

Cite this

@article{f2d34b543fdf43128c8331c9b42f88ae,

title = "Base and solvent dependency of an oxidative retro-alkylation of secondary and tertiary benzylamines",

abstract = "An iodine and caesium carbonate amine oxidation protocol is described. Non-branched secondary benzylamines were cleanly oxidised to aldimines that could be isolated without the need for chromatography. A tertiary amine bearing an ethyl group was oxidatively de-ethylated by iodine and caesium carbonate in a DMSO-water solvent system.",

author = "A. Feula and J.S. Fossey",

year = "2013",

month = apr,

day = "28",

doi = "10.1039/c3ra40228b",

language = "English",

volume = "3",

pages = "5370--5373",

journal = "RSC Advances",

issn = "2046-2069",

publisher = "Royal Society of Chemistry",

number = "16",

}

TY - JOUR

T1 - Base and solvent dependency of an oxidative retro-alkylation of secondary and tertiary benzylamines

AU - Feula, A.

AU - Fossey, J.S.

PY - 2013/4/28

Y1 - 2013/4/28

N2 - An iodine and caesium carbonate amine oxidation protocol is described. Non-branched secondary benzylamines were cleanly oxidised to aldimines that could be isolated without the need for chromatography. A tertiary amine bearing an ethyl group was oxidatively de-ethylated by iodine and caesium carbonate in a DMSO-water solvent system.

AB - An iodine and caesium carbonate amine oxidation protocol is described. Non-branched secondary benzylamines were cleanly oxidised to aldimines that could be isolated without the need for chromatography. A tertiary amine bearing an ethyl group was oxidatively de-ethylated by iodine and caesium carbonate in a DMSO-water solvent system.

UR - http://www.scopus.com/inward/record.url?eid=2-s2.0-84878074508&partnerID=8YFLogxK

U2 - 10.1039/c3ra40228b

DO - 10.1039/c3ra40228b

M3 - Article

AN - SCOPUS:84878074508

SN - 2046-2069

VL - 3

SP - 5370

EP - 5373

JO - RSC Advances

JF - RSC Advances

IS - 16

ER -

Base and solvent dependency of an oxidative retro-alkylation of secondary and tertiary benzylamines

Abstract

Access to Document

Fingerprint

Cite this