Abstract
Atrial fibrillation (AF) is associated with an increased risk of mortality and morbidity from stroke and thromboembolism. Endothelial damage or dysfunction may contribute to this increased risk of thromboembolism via the mediation of a prothrombotic or hypercoagulable state. However, the precise pathophysiological mechanism(s) relating endothelial (dys)function to AF and thromboembolism are yet to be fully elucidated. This review article aims to provide a comprehensive overview of endothelial (dys)function and AF, as well as the merits and limitations of the different methods used to assess endothelial function in AF.
| Original language | English |
|---|---|
| Pages (from-to) | 1-15 |
| Number of pages | 15 |
| Journal | Annals of Medicine |
| DOIs | |
| Publication status | Published - 26 Aug 2009 |
Keywords
- von Willebrand factor
- endothelium
- diabetes mellitus
- cardiovascular disease
- endothelial function
- Acute myocardial infarction
- endothelial dysfunction
- impaired glucose tolerance
- flow-mediated dilatation
- Atrial fibrillation
- circulating endothelial cells
