Assessment of endothelial dysfunction.

B Freestone, Suresh Krishnamoorthy, Gregory Lip

Research output: Contribution to journalReview article

14 Citations (Scopus)


The pathophysiology underlying the initiation and progression of cardiovascular disorders is highly complex and multifactorial. The endothelium also plays a crucial role in the pathogenesis of thrombogenesis and atherogenesis, and a continuum of endothelial activation, dysfunction or damage is evident in many cardiovascular disorders both at the macro and microscopic level(s). This review article aims to provide an overview of the assessment of endothelial (dys)function and discuss the implications and limitations of such assessments.
Original languageEnglish
Pages (from-to)557-71
Number of pages15
JournalExpert review of cardiovascular therapy
Issue number4
Publication statusPublished - 1 Apr 2010


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