Assessing the welfare of genetically altered mice

DJ Wells; LC Playle; WEJ Enser; PA Flecknell; MA Gardiner; J Holland; BR Howard; R Hubrecht; KR Humphreys; IJ Jackson; N Lane; M Maconochie; David Morton; R Raymond; V Robinson; JA Smith; N Watt; Georgia J Mason

doi:10.1258/002367706776318971

Assessing the welfare of genetically altered mice

DJ Wells
, LC Playle
, WEJ Enser
, PA Flecknell
, MA Gardiner
, J Holland
, BR Howard
, R Hubrecht
, KR Humphreys
, IJ Jackson
, N Lane
, M Maconochie
, David Morton
, R Raymond
, V Robinson
, JA Smith
, N Watt
, Georgia J Mason

Research output: Contribution to journal › Article

51 Citations (Scopus)

Abstract

In 2003, under the auspices of the main UK funders of biological and biomedical research, a working group was established with a remit to review potential welfare issues for genetically altered (GA) mice, to summarize current practice, and to recommend contemporary best practice for welfare assessments. The working group has produced a report which makes practical recommendations for GA mouse welfare assessment and dissemination of welfare information between establishments using a 'mouse passport'. The report can be found at www.nc3rs.org.uk/GAmice and www.lal.org.uk/gaa and includes templates for the recommended welfare assessment scheme and the mouse passport. An overview is provided below.

Original language	English
Pages (from-to)	111-114
Number of pages	4
Journal	Laboratory Animals
Volume	40
Issue number	2
DOIs	https://doi.org/10.1258/002367706776318971
Publication status	Published - 1 Apr 2006

Keywords

mouse
genetic modification
welfare assessment
genetic alteration
passport

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10.1258/002367706776318971

Cite this

Wells, DJ., Playle, LC., Enser, WEJ., Flecknell, PA., Gardiner, MA., Holland, J., Howard, BR., Hubrecht, R., Humphreys, KR., Jackson, IJ., Lane, N., Maconochie, M., Morton, D., Raymond, R., Robinson, V., Smith, JA., Watt, N., & Mason, G. J. (2006). Assessing the welfare of genetically altered mice. Laboratory Animals, 40(2), 111-114. https://doi.org/10.1258/002367706776318971

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abstract = "In 2003, under the auspices of the main UK funders of biological and biomedical research, a working group was established with a remit to review potential welfare issues for genetically altered (GA) mice, to summarize current practice, and to recommend contemporary best practice for welfare assessments. The working group has produced a report which makes practical recommendations for GA mouse welfare assessment and dissemination of welfare information between establishments using a 'mouse passport'. The report can be found at www.nc3rs.org.uk/GAmice and www.lal.org.uk/gaa and includes templates for the recommended welfare assessment scheme and the mouse passport. An overview is provided below.",

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Wells, DJ, Playle, LC, Enser, WEJ, Flecknell, PA, Gardiner, MA, Holland, J, Howard, BR, Hubrecht, R, Humphreys, KR, Jackson, IJ, Lane, N, Maconochie, M, Morton, D, Raymond, R, Robinson, V, Smith, JA, Watt, N & Mason, GJ 2006, 'Assessing the welfare of genetically altered mice', Laboratory Animals, vol. 40, no. 2, pp. 111-114. https://doi.org/10.1258/002367706776318971

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T1 - Assessing the welfare of genetically altered mice

AU - Wells, DJ

AU - Playle, LC

AU - Enser, WEJ

AU - Flecknell, PA

AU - Gardiner, MA

AU - Holland, J

AU - Howard, BR

AU - Hubrecht, R

AU - Humphreys, KR

AU - Jackson, IJ

AU - Lane, N

AU - Maconochie, M

AU - Morton, David

AU - Raymond, R

AU - Robinson, V

AU - Smith, JA

AU - Watt, N

AU - Mason, Georgia J

PY - 2006/4/1

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N2 - In 2003, under the auspices of the main UK funders of biological and biomedical research, a working group was established with a remit to review potential welfare issues for genetically altered (GA) mice, to summarize current practice, and to recommend contemporary best practice for welfare assessments. The working group has produced a report which makes practical recommendations for GA mouse welfare assessment and dissemination of welfare information between establishments using a 'mouse passport'. The report can be found at www.nc3rs.org.uk/GAmice and www.lal.org.uk/gaa and includes templates for the recommended welfare assessment scheme and the mouse passport. An overview is provided below.

AB - In 2003, under the auspices of the main UK funders of biological and biomedical research, a working group was established with a remit to review potential welfare issues for genetically altered (GA) mice, to summarize current practice, and to recommend contemporary best practice for welfare assessments. The working group has produced a report which makes practical recommendations for GA mouse welfare assessment and dissemination of welfare information between establishments using a 'mouse passport'. The report can be found at www.nc3rs.org.uk/GAmice and www.lal.org.uk/gaa and includes templates for the recommended welfare assessment scheme and the mouse passport. An overview is provided below.

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KW - welfare assessment

KW - genetic alteration

KW - passport

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VL - 40

SP - 111

EP - 114

JO - Laboratory Animals

JF - Laboratory Animals

IS - 2

ER -

Assessing the welfare of genetically altered mice

Abstract

Keywords

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