Assessing the welfare of genetically altered mice

DJ Wells; LC Playle; WEJ Enser; PA Flecknell; MA Gardiner; J Holland; BR Howard; R Hubrecht; KR Humphreys; IJ Jackson; N Lane; M Maconochie; David Morton; R Raymond; V Robinson; JA Smith; N Watt; Georgia J Mason

doi:10.1258/002367706776318971

Assessing the welfare of genetically altered mice

DJ Wells, LC Playle, WEJ Enser, PA Flecknell, MA Gardiner, J Holland, BR Howard, R Hubrecht, KR Humphreys, IJ Jackson, N Lane, M Maconochie, David Morton, R Raymond, V Robinson, JA Smith, N Watt, Georgia J Mason

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Abstract

In 2003, under the auspices of the main UK funders of biological and biomedical research, a working group was established with a remit to review potential welfare issues for genetically altered (GA) mice, to summarize current practice, and to recommend contemporary best practice for welfare assessments. The working group has produced a report which makes practical recommendations for GA mouse welfare assessment and dissemination of welfare information between establishments using a 'mouse passport'. The report can be found at www.nc3rs.org.uk/GAmice and www.lal.org.uk/gaa and includes templates for the recommended welfare assessment scheme and the mouse passport. An overview is provided below.

Original language	English
Pages (from-to)	111-114
Number of pages	4
Journal	Laboratory Animals
Volume	40
Issue number	2
DOIs	https://doi.org/10.1258/002367706776318971
Publication status	Published - 1 Apr 2006

Keywords

mouse
genetic modification
welfare assessment
genetic alteration
passport

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10.1258/002367706776318971

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Wells, DJ., Playle, LC., Enser, WEJ., Flecknell, PA., Gardiner, MA., Holland, J., Howard, BR., Hubrecht, R., Humphreys, KR., Jackson, IJ., Lane, N., Maconochie, M., Morton, D., Raymond, R., Robinson, V., Smith, JA., Watt, N., & Mason, G. J. (2006). Assessing the welfare of genetically altered mice. Laboratory Animals, 40(2), 111-114. https://doi.org/10.1258/002367706776318971

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abstract = "In 2003, under the auspices of the main UK funders of biological and biomedical research, a working group was established with a remit to review potential welfare issues for genetically altered (GA) mice, to summarize current practice, and to recommend contemporary best practice for welfare assessments. The working group has produced a report which makes practical recommendations for GA mouse welfare assessment and dissemination of welfare information between establishments using a 'mouse passport'. The report can be found at www.nc3rs.org.uk/GAmice and www.lal.org.uk/gaa and includes templates for the recommended welfare assessment scheme and the mouse passport. An overview is provided below.",

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Wells, DJ, Playle, LC, Enser, WEJ, Flecknell, PA, Gardiner, MA, Holland, J, Howard, BR, Hubrecht, R, Humphreys, KR, Jackson, IJ, Lane, N, Maconochie, M, Morton, D, Raymond, R, Robinson, V, Smith, JA, Watt, N & Mason, GJ 2006, 'Assessing the welfare of genetically altered mice', Laboratory Animals, vol. 40, no. 2, pp. 111-114. https://doi.org/10.1258/002367706776318971

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T1 - Assessing the welfare of genetically altered mice

AU - Wells, DJ

AU - Playle, LC

AU - Enser, WEJ

AU - Flecknell, PA

AU - Gardiner, MA

AU - Holland, J

AU - Howard, BR

AU - Hubrecht, R

AU - Humphreys, KR

AU - Jackson, IJ

AU - Lane, N

AU - Maconochie, M

AU - Morton, David

AU - Raymond, R

AU - Robinson, V

AU - Smith, JA

AU - Watt, N

AU - Mason, Georgia J

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N2 - In 2003, under the auspices of the main UK funders of biological and biomedical research, a working group was established with a remit to review potential welfare issues for genetically altered (GA) mice, to summarize current practice, and to recommend contemporary best practice for welfare assessments. The working group has produced a report which makes practical recommendations for GA mouse welfare assessment and dissemination of welfare information between establishments using a 'mouse passport'. The report can be found at www.nc3rs.org.uk/GAmice and www.lal.org.uk/gaa and includes templates for the recommended welfare assessment scheme and the mouse passport. An overview is provided below.

AB - In 2003, under the auspices of the main UK funders of biological and biomedical research, a working group was established with a remit to review potential welfare issues for genetically altered (GA) mice, to summarize current practice, and to recommend contemporary best practice for welfare assessments. The working group has produced a report which makes practical recommendations for GA mouse welfare assessment and dissemination of welfare information between establishments using a 'mouse passport'. The report can be found at www.nc3rs.org.uk/GAmice and www.lal.org.uk/gaa and includes templates for the recommended welfare assessment scheme and the mouse passport. An overview is provided below.

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KW - welfare assessment

KW - genetic alteration

KW - passport

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VL - 40

SP - 111

EP - 114

JO - Laboratory Animals

JF - Laboratory Animals

IS - 2

ER -

Assessing the welfare of genetically altered mice

Abstract

Keywords

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