Assessing the welfare of genetically altered mice

DJ Wells, LC Playle, WEJ Enser, PA Flecknell, MA Gardiner, J Holland, BR Howard, R Hubrecht, KR Humphreys, IJ Jackson, N Lane, M Maconochie, David Morton, R Raymond, V Robinson, JA Smith, N Watt, Georgia J Mason

    Research output: Contribution to journalArticle

    51 Citations (Scopus)

    Abstract

    In 2003, under the auspices of the main UK funders of biological and biomedical research, a working group was established with a remit to review potential welfare issues for genetically altered (GA) mice, to summarize current practice, and to recommend contemporary best practice for welfare assessments. The working group has produced a report which makes practical recommendations for GA mouse welfare assessment and dissemination of welfare information between establishments using a 'mouse passport'. The report can be found at www.nc3rs.org.uk/GAmice and www.lal.org.uk/gaa and includes templates for the recommended welfare assessment scheme and the mouse passport. An overview is provided below.
    Original languageEnglish
    Pages (from-to)111-114
    Number of pages4
    JournalLaboratory Animals
    Volume40
    Issue number2
    DOIs
    Publication statusPublished - 1 Apr 2006

    Keywords

    • mouse
    • genetic modification
    • welfare assessment
    • genetic alteration
    • passport

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