Assess drug-resistance phenotypes, not just genotypes.

Laura Piddock

doi:10.1038/nmicrobiol.2016.120

Assess drug-resistance phenotypes, not just genotypes.

Laura Piddock

Research output: Contribution to journal › Comment/debate › peer-review

22 Citations (Scopus)

352 Downloads (Pure)

Abstract

Whole genome sequencing is often used to determine the presence of known antimicrobial resistance genes and identify new resistance mechanisms. However, without phenotypic confirmation of resistance, caution needs to be taken in attributing relevance to any genes hitherto not shown to confer drug resistance.

Original language	English
Article number	16120
Number of pages	2
Journal	Nature Microbiology
Volume	1
Early online date	26 Jul 2016
DOIs	https://doi.org/10.1038/nmicrobiol.2016.120
Publication status	Published - 2016

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title = "Assess drug-resistance phenotypes, not just genotypes.",

abstract = "Whole genome sequencing is often used to determine the presence of known antimicrobial resistance genes and identify new resistance mechanisms. However, without phenotypic confirmation of resistance, caution needs to be taken in attributing relevance to any genes hitherto not shown to confer drug resistance.",

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journal = "Nature Microbiology",

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AB - Whole genome sequencing is often used to determine the presence of known antimicrobial resistance genes and identify new resistance mechanisms. However, without phenotypic confirmation of resistance, caution needs to be taken in attributing relevance to any genes hitherto not shown to confer drug resistance.

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U2 - 10.1038/nmicrobiol.2016.120

DO - 10.1038/nmicrobiol.2016.120

M3 - Comment/debate

SN - 2058-5276

VL - 1

JO - Nature Microbiology

JF - Nature Microbiology

M1 - 16120

ER -

Assess drug-resistance phenotypes, not just genotypes.

Abstract

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