Armadillo-repeat protein functions: questions for little creatures

R Tewari; E Bailes; KA Bunting; Juliet Coates

doi:10.1016/j.tcb.2010.05.003

Armadillo-repeat protein functions: questions for little creatures

R Tewari, E Bailes, KA Bunting, Juliet Coates

Biosciences

Research output: Contribution to journal › Review article › peer-review

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Abstract

Armadillo (ARK-repeat proteins form a large family with diverse and fundamental functions in many eukaryotes. ARM-repeat proteins have largely been characterised in multicellular organisms and much is known about how a subset of these proteins function. The structure of ARM-repeats allows proteins containing them to be functionally very versatile. Are the ARM-repeat proteins in 'little creatures' as multifunctional as their better-studied relatives? The time is now right to start analysing ARM-repeat proteins in these new systems to better understand their cell biology. Here, we review recent advances in understanding the many cellular roles of both well-known and novel ARM-repeat proteins.

Original language	English
Pages (from-to)	470-481
Number of pages	12
Journal	Trends in Cell Biology
Volume	20
Issue number	8
DOIs	https://doi.org/10.1016/j.tcb.2010.05.003
Publication status	Published - 1 Aug 2010

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AB - Armadillo (ARK-repeat proteins form a large family with diverse and fundamental functions in many eukaryotes. ARM-repeat proteins have largely been characterised in multicellular organisms and much is known about how a subset of these proteins function. The structure of ARM-repeats allows proteins containing them to be functionally very versatile. Are the ARM-repeat proteins in 'little creatures' as multifunctional as their better-studied relatives? The time is now right to start analysing ARM-repeat proteins in these new systems to better understand their cell biology. Here, we review recent advances in understanding the many cellular roles of both well-known and novel ARM-repeat proteins.

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JO - Trends in Cell Biology

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Armadillo-repeat protein functions: questions for little creatures

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