Are polyphosphoinositides associated with glycophorin in human erythrocyte membrane?

SD Shukla, R Coleman, JB Finean, RH Michell

Research output: Contribution to journalArticlepeer-review

17 Citations (Scopus)

Abstract

Glycophorin prepared by a lithium di-iodosalicylate-extraction/phenol-partition method was rich in polyphosphoinositides (phosphatidyl-myo-inositol 4-phosphate and phosphatidyl-myo-inositol 4,5-bisphosphate), but glycophorin extracted by Triton X-100 showed no such enrichment. The enrichment observed in the former preparations appeared not to be caused by pre-existing association between glycophorin and polyphosphoinositides in the human erythrocyte membrane, but to be largely a consequence of the preparative procedures.

Original languageEnglish
Pages (from-to)441-444
Number of pages4
JournalBiochemical Journal
Volume179
Issue number2
DOIs
Publication statusPublished - 1 May 1979

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Cell Biology

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