Anti-inflammatory and immunosuppressive drugs and reproduction

M Ostensen, M Khamashta, M Lockshin, A Parke, A Brucato, H Carp, A Doria, R Rai, P Meroni, I Cetin, R Derksen, W Branch, M Motta, Caroline Gordon

Research output: Contribution to journalReview article

389 Citations (Scopus)


Rheumatic diseases in women of childbearing years may necessitate drug treatment during a pregnancy, to control maternal disease activity and to ensure a successful pregnancy outcome. This survey is based on a consensus workshop of international experts discussing effects of anti-inflammatory, immunosuppressive and biological drugs during pregnancy and lactation. In addition, effects of these drugs on male and female fertility and possible long-term effects on infants exposed to drugs antenatally are discussed where data were available. Recommendations for drug treatment during pregnancy and lactation are given.
Original languageEnglish
Pages (from-to)209-
JournalArthritis Research & Therapy
Publication statusPublished - 1 Jan 2006


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