Angle-Resolved Particle Image Velocimetry Measurements of Flow and Turbulence Fields in Small-Scale Stirred Vessels of Different Mixer Configurations

Angle-resolved particle image velocimetry measurements were conducted at one degree intervals in miniature vessels of four different configurations used in high-throughput experimentation. The four vessels-standard fully baffled, unbaffled, off-center or eccentric impeller, and square section-were agitated by an up-pumping six-blade 45 degrees pitched blade turbine (PBT). The effect of periodicity was revealed in all configurations but was restricted to the impeller discharge and inflow regions. The square vessel achieved the strongest axial-radial flow field among all configurations. The smallest overestimation in the computation of turbulent kinetic energy by the ensemble time average method, otherwise referred to as pseudoturbulence, was achieved in the eccentric and square configurations. The up-pumping PBT shed trailing vortices mainly in a radial direction with relatively little axial movement. The highest axial vortex position was achieved in the square vessel, which may be partly responsible for its lower mixing time compared to other configurations. The measurements obtained here in the high-transitional regime suggest that the square configuration perforrns better than other configurations and can be a good replacement for the fully baffled vessel in commercial high-throughput experimentation units where baffles are usually prohibited. This result was confirmed from mixing time measurements made using planar laser induced fluorescence where the superiority of the square vessel was demonstrated.