TY - JOUR
T1 - An abundance of bacterial ADP-ribosyltransferases - implications for the origin of exotoxins and their human homologues
AU - Pallen, Mark
AU - Lam, AC
AU - Loman, NJ
AU - McBridge, A
PY - 2001/7/1
Y1 - 2001/7/1
N2 - ADP-ribosylation is a post-translational modification that can be seen in many contexts, including as the primary mechanism of action of many important bacterial exotoxins, By data-mining complete and incomplete bacterial genome sequences, we have discovered > 20 novel putative ADP-ribosyltransferases. including several new potential toxins.
AB - ADP-ribosylation is a post-translational modification that can be seen in many contexts, including as the primary mechanism of action of many important bacterial exotoxins, By data-mining complete and incomplete bacterial genome sequences, we have discovered > 20 novel putative ADP-ribosyltransferases. including several new potential toxins.
UR - http://www.scopus.com/inward/record.url?scp=0035400143&partnerID=8YFLogxK
U2 - 10.1016/S0966-842X(01)02074-1
DO - 10.1016/S0966-842X(01)02074-1
M3 - Article
VL - 9
SP - 302
EP - 307
JO - Trends in Microbiology
JF - Trends in Microbiology
IS - 7
ER -