Alpha phase locking predicts residual working memory performance in schizophrenia

Corinna Haenschel, David E Linden, Robert A Bittner, Wolf Singer, Simon Hanslmayr

Research output: Contribution to journalArticlepeer-review

33 Citations (Scopus)

Abstract

Working memory (WM) deficits are a core feature of schizophrenia. Recent electrophysiological evidence indicates that the brain systems for visual encoding are especially impaired. However, patients still achieve performance levels clearly above chance, which indicates the existence of residual mechanisms supporting WM encoding. The present study presents evidence that alpha phase locking of the electroencephalogram is a marker for such residual cognitive mechanisms.
Original languageEnglish
Pages (from-to)595-8
Number of pages4
JournalBiological Psychiatry
Volume68
Issue number7
DOIs
Publication statusPublished - 1 Oct 2010

Keywords

  • Alpha Rhythm
  • Analysis of Variance
  • Brain Mapping
  • Discrimination (Psychology)
  • Electroencephalography
  • Humans
  • Memory Disorders
  • Memory, Short-Term
  • Neuropsychological Tests
  • Predictive Value of Tests
  • Reaction Time
  • Schizophrenia
  • Schizophrenic Psychology
  • Time Factors

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