Age-associated increase of codon 72 Arginine p53 frequency in gastric cardia and non-cardia adenocarcinoma

Zun-Wu Zhang; Paul Newcomb; Andrew Hollowood; Roger Feakins; Moganaden Moorghen; Alan Storey; Michael J G Farthing; Derek Alderson; Jeff Holly

Age-associated increase of codon 72 Arginine p53 frequency in gastric cardia and non-cardia adenocarcinoma

Zun-Wu Zhang, Paul Newcomb, Andrew Hollowood, Roger Feakins, Moganaden Moorghen, Alan Storey, Michael J G Farthing, Derek Alderson, Jeff Holly

Cancer and Genomic Sciences

Research output: Contribution to journal › Article › peer-review

49 Citations (Scopus)

Abstract

A common polymorphism of the tumor suppressor gene TP53 at codon 72 has been associated with human cancer susceptibility and prognosis. To examine the role of the polymorphism in the gastric adenocarcinoma, we examined 397 patients with or without the cancer.

Original language	English
Pages (from-to)	2151-6
Number of pages	6
Journal	Clinical Cancer Research
Volume	9
Issue number	6
Publication status	Published - 2003

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title = "Age-associated increase of codon 72 Arginine p53 frequency in gastric cardia and non-cardia adenocarcinoma",

abstract = "A common polymorphism of the tumor suppressor gene TP53 at codon 72 has been associated with human cancer susceptibility and prognosis. To examine the role of the polymorphism in the gastric adenocarcinoma, we examined 397 patients with or without the cancer.",

author = "Zun-Wu Zhang and Paul Newcomb and Andrew Hollowood and Roger Feakins and Moganaden Moorghen and Alan Storey and Farthing, {Michael J G} and Derek Alderson and Jeff Holly",

year = "2003",

language = "English",

volume = "9",

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journal = "Clinical Cancer Research",

issn = "1078-0432",

publisher = "American Association for Cancer Research",

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T1 - Age-associated increase of codon 72 Arginine p53 frequency in gastric cardia and non-cardia adenocarcinoma

AU - Zhang, Zun-Wu

AU - Newcomb, Paul

AU - Hollowood, Andrew

AU - Feakins, Roger

AU - Moorghen, Moganaden

AU - Storey, Alan

AU - Farthing, Michael J G

AU - Alderson, Derek

AU - Holly, Jeff

PY - 2003

Y1 - 2003

N2 - A common polymorphism of the tumor suppressor gene TP53 at codon 72 has been associated with human cancer susceptibility and prognosis. To examine the role of the polymorphism in the gastric adenocarcinoma, we examined 397 patients with or without the cancer.

AB - A common polymorphism of the tumor suppressor gene TP53 at codon 72 has been associated with human cancer susceptibility and prognosis. To examine the role of the polymorphism in the gastric adenocarcinoma, we examined 397 patients with or without the cancer.

M3 - Article

C2 - 12796380

SN - 1078-0432

VL - 9

SP - 2151

EP - 2156

JO - Clinical Cancer Research

JF - Clinical Cancer Research

IS - 6

ER -

Age-associated increase of codon 72 Arginine p53 frequency in gastric cardia and non-cardia adenocarcinoma

Abstract

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