TY - JOUR
T1 - Advances in nanoreactor technology using polymeric nanostructures
AU - Lu, Annhelen
AU - O'Reilly, Rachel K.
PY - 2013/8
Y1 - 2013/8
N2 - Site isolation, compartmentalization and substrate specificity are a few of the characteristics responsible for the catalytic efficiency demonstrated by enzymes in natural systems. In efforts to mimic these highly efficient systems, research has been directed towards macromolecular chemistry. Robust polymer assemblies can create a favorable and isolated environment around the catalytic site allowing specific and sometimes incompatible reactions to take place within this protected reaction pocket. Further exploring the use of ‘smart’ polymers, control over both the catalytic activity and substrate specificity is achieved. In addition, polymeric systems provide the opportunity for recycling of the active catalysts, further enhancing the advantages of polymer supported catalytic systems.
AB - Site isolation, compartmentalization and substrate specificity are a few of the characteristics responsible for the catalytic efficiency demonstrated by enzymes in natural systems. In efforts to mimic these highly efficient systems, research has been directed towards macromolecular chemistry. Robust polymer assemblies can create a favorable and isolated environment around the catalytic site allowing specific and sometimes incompatible reactions to take place within this protected reaction pocket. Further exploring the use of ‘smart’ polymers, control over both the catalytic activity and substrate specificity is achieved. In addition, polymeric systems provide the opportunity for recycling of the active catalysts, further enhancing the advantages of polymer supported catalytic systems.
UR - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000323298200013&KeyUID=WOS:000323298200013
U2 - 10.1016/j.copbio.2012.11.013
DO - 10.1016/j.copbio.2012.11.013
M3 - Article
SN - 0958-1669
VL - 24
SP - 639
EP - 645
JO - Current Opinion in Biotechnology
JF - Current Opinion in Biotechnology
IS - 4
ER -