TY - JOUR
T1 - Adjuvant materials in anterior vaginal wall prolapse surgery: a systematic review of effectiveness and complications.
AU - Foon, Richard
AU - Toozs-Hobson, Philip
AU - Latthe, Pallavi
PY - 2008/12/1
Y1 - 2008/12/1
N2 - The objective of this study is to assess the objective recurrence and complications of adjuvant materials in the treatment of anterior vaginal wall prolapse. The inclusion criteria were randomised controlled trials (RCTs) using adjuvant materials versus standard surgery for anterior vaginal wall prolapse. The main outcome measures were objective recurrence and complications. Ten RCTs (1,087 patients) were included in the systematic review. Meta-analysis showed a lower risk of objective recurrence after 1 year in the patients having an anterior repair with a biological adjuvant material (odds ratio 0.56; 95% confidence interval 0.34-0.92) and absorbable synthetic adjuvant material (odds ratio 0.44; 95% confidence interval 0.21-0.89). The evidence for the use of biological adjuvant materials in anterior vaginal wall prolapse surgery shows trends towards reduction of objective recurrence at 12 months.
AB - The objective of this study is to assess the objective recurrence and complications of adjuvant materials in the treatment of anterior vaginal wall prolapse. The inclusion criteria were randomised controlled trials (RCTs) using adjuvant materials versus standard surgery for anterior vaginal wall prolapse. The main outcome measures were objective recurrence and complications. Ten RCTs (1,087 patients) were included in the systematic review. Meta-analysis showed a lower risk of objective recurrence after 1 year in the patients having an anterior repair with a biological adjuvant material (odds ratio 0.56; 95% confidence interval 0.34-0.92) and absorbable synthetic adjuvant material (odds ratio 0.44; 95% confidence interval 0.21-0.89). The evidence for the use of biological adjuvant materials in anterior vaginal wall prolapse surgery shows trends towards reduction of objective recurrence at 12 months.
U2 - 10.1007/s00192-008-0668-x
DO - 10.1007/s00192-008-0668-x
M3 - Review article
C2 - 18607524
SN - 1433-3023
SN - 1433-3023
SN - 1433-3023
SN - 1433-3023
SN - 1433-3023
SN - 1433-3023
SN - 1433-3023
SN - 1433-3023
VL - 19
SP - 1697
EP - 1706
JO - International urogynecology journal and pelvic floor dysfunction
JF - International urogynecology journal and pelvic floor dysfunction
IS - 12
ER -