Acute systemic hypoxia and the surface ultrastructure and morphological characteristics of rat leucocytes

R. Mian; D. Westwood; P. Stanley; JM Marshall; JH Coote

doi:10.1113/expphysiol.1993.sp003731

Acute systemic hypoxia and the surface ultrastructure and morphological characteristics of rat leucocytes

R. Mian^*
, D. Westwood
, P. Stanley
, JM Marshall
, JH Coote

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

We have examined the surface ultrastructure and morphological characteristics of leucocytes obtained from control rats breathing air and rats made acutely hypoxic (breathing 6% O2, for 30 min). Striking ultrastructural and morphological changes occurred in the leucocytes of hypoxic rats. These changes included the appearance of crater‐like holes, a reduction in granule size and disruption of the cell membrane. The implications of these findings are discussed.

Original language	English
Pages (from-to)	839-842
Number of pages	4
Journal	Experimental Physiology
Volume	78
Issue number	6
DOIs	https://doi.org/10.1113/expphysiol.1993.sp003731
Publication status	Published - 1 Nov 1993

ASJC Scopus subject areas

Physiology
Nutrition and Dietetics
Physiology (medical)

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10.1113/expphysiol.1993.sp003731

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abstract = "We have examined the surface ultrastructure and morphological characteristics of leucocytes obtained from control rats breathing air and rats made acutely hypoxic (breathing 6\% O2, for 30 min). Striking ultrastructural and morphological changes occurred in the leucocytes of hypoxic rats. These changes included the appearance of crater‐like holes, a reduction in granule size and disruption of the cell membrane. The implications of these findings are discussed.",

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AU - Mian, R.

AU - Westwood, D.

AU - Stanley, P.

AU - Marshall, JM

AU - Coote, JH

PY - 1993/11/1

Y1 - 1993/11/1

N2 - We have examined the surface ultrastructure and morphological characteristics of leucocytes obtained from control rats breathing air and rats made acutely hypoxic (breathing 6% O2, for 30 min). Striking ultrastructural and morphological changes occurred in the leucocytes of hypoxic rats. These changes included the appearance of crater‐like holes, a reduction in granule size and disruption of the cell membrane. The implications of these findings are discussed.

AB - We have examined the surface ultrastructure and morphological characteristics of leucocytes obtained from control rats breathing air and rats made acutely hypoxic (breathing 6% O2, for 30 min). Striking ultrastructural and morphological changes occurred in the leucocytes of hypoxic rats. These changes included the appearance of crater‐like holes, a reduction in granule size and disruption of the cell membrane. The implications of these findings are discussed.

UR - https://www.scopus.com/pages/publications/0027692692

U2 - 10.1113/expphysiol.1993.sp003731

DO - 10.1113/expphysiol.1993.sp003731

M3 - Article

C2 - 8311950

AN - SCOPUS:0027692692

SN - 0958-0670

VL - 78

SP - 839

EP - 842

JO - Experimental Physiology

JF - Experimental Physiology

IS - 6

ER -

Acute systemic hypoxia and the surface ultrastructure and morphological characteristics of rat leucocytes

Abstract

ASJC Scopus subject areas

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