Acute systemic hypoxia and the surface ultrastructure and morphological characteristics of rat leucocytes

R. Mian*, D. Westwood, P. Stanley, JM Marshall, JH Coote

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)

Abstract

We have examined the surface ultrastructure and morphological characteristics of leucocytes obtained from control rats breathing air and rats made acutely hypoxic (breathing 6% O2, for 30 min). Striking ultrastructural and morphological changes occurred in the leucocytes of hypoxic rats. These changes included the appearance of crater‐like holes, a reduction in granule size and disruption of the cell membrane. The implications of these findings are discussed.

Original languageEnglish
Pages (from-to)839-842
Number of pages4
JournalExperimental Physiology
Volume78
Issue number6
DOIs
Publication statusPublished - 1 Nov 1993

ASJC Scopus subject areas

  • Physiology
  • Nutrition and Dietetics
  • Physiology (medical)

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