Active-metal template synthesis of a molecular trefoil knot

Perdita E. Barran, Harriet L. Cole, Stephen M. Goldup, David A. Leigh*, Paul R. McGonigal, Mark D. Symes, Jhenyi Wu, Michael Zengerle

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

120 Citations (Scopus)

Abstract

Tying the knot: The marriage of catalysis and coordination chemistry enables two Cu I ions (red; see picture) to work in partnership for the synthesis of a molecular trefoil knot. One ion entangles an acyclic building block to create a loop in the ligand, and the other gathers the ligand's reactive end-groups, threads the loop, and catalyzes the covalent capture of the knotted architecture by an alkyne-azide "click" reaction.

Original languageEnglish
Pages (from-to)12280-12284
Number of pages5
JournalAngewandte Chemie - International Edition
Volume50
Issue number51
DOIs
Publication statusPublished - 16 Dec 2011

Keywords

  • chemical topology
  • click chemistry
  • self-assembly
  • supramolecular chemistry
  • template synthesis

ASJC Scopus subject areas

  • Catalysis
  • General Chemistry

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