AcrB drug-binding pocket substitution confers clinically relevant resistance and altered substrate specificity

Jessica M. A. Blair, Vassiliy N. Bavro, Vito Ricci, Niraj Modi, Pierpaolo Cacciotto, Ulrich Kleinekathӧfer, Paolo Ruggerone, Attilio V. Vargiu, Alison J. Baylay, Helen E. Smith, Yvonne Brandon, David Galloway, Laura J. V. Piddock