Achieving minimal residual disease (MRD) negativity in CLL is independently associated with improved progression-free and overall survival and is an appropriate end-point of therapy

Marwan Cheng Kuang Kwok, Andy C Rawstron, Abraham Varghese, Peter Hillmen

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Eradication of detectable minimal residual disease (MRD) in CLL is associated with improved progression-free and overall survival. Herewe present the first multivariate analysis from 137 responding CLLpatients treated between 1996 and 2007 with bone marrow MRD assessment by multicolour flow cytometry (sensitivity: 1 CLL cell in10,000 leukocytes [HMDS]).
Original languageEnglish
Title of host publicationBritish Journal of Haematology
Pages20
Number of pages21
Volume149
Publication statusPublished - 2010

Publication series

NameBritish Journal of Haematology
PublisherWiley
ISSN (Print)0007-1048

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