Accuracy of routine laboratory tests to predict mortality and deterioration to severe or critical COVID-19 in people with SARS-CoV-2 (Protocol)

  • Cochrane COVID-19 Diagnostic Test Accuracy Group
  • , Jan Y Verbakel*
  • , Liselore De Rop
  • , Inge Stegeman
  • , Gea A Holtman
  • , Eleanor A Ochodo
  • , Bada Yang
  • , Fatuma Guleid
  • , Clare Davenport
  • , Jonathan J Deeks
  • , Jacqueline Dinnes
  • , Sabine Dittrich
  • , Devy Emperador
  • , Lotty Hooft
  • , René Spijker
  • , Ann Van den Bruel
  • , Junfeng Wang
  • , Yemisi Takwoingi
  • , Miranda W Langendam
  • , Mariska MG Leeflang
  • *Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Objectives:

This is a protocol for a Cochrane Review (diagnostic). The objectives are as follows:

To assess the accuracy of routine blood‐based laboratory tests to predict mortality and deterioration to severe or critical (from mild or moderate) COVID‐19 in people with SARS‐CoV‐2 infection.

Secondary objectives:

Where data are available, we will investigate whether prognostic accuracy varies according to a specific measurement or test, reference standard, timing of outcome verification, sample type, study design, and setting, including prevalence of the target condition (either by stratified analysis or meta‐regression).

Original languageEnglish
Article numberCD015050
Number of pages11
JournalCochrane Database of Systematic Reviews
Volume2021
Issue number9
DOIs
Publication statusPublished - 17 Sept 2021

Bibliographical note

Publisher Copyright:
Copyright © 2021 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.

ASJC Scopus subject areas

  • Pharmacology (medical)

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