A three-compartment chemically-driven molecular information ratchet

Armando Carlone, Stephen M. Goldup, Nathalie Lebrasseur, David A. Leigh*, Adam Wilson

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

94 Citations (Scopus)


We describe a three-compartment rotaxane information ratchet in which the macrocycle can be directionally transported in either direction along an achiral (disregarding isotopic labeling) track. Chiral DMAP-based catalysts promote a benzoylation reaction that ratchets the displacement of the macrocycle, transporting it predominantly to a particular end compartment determined by the handedness of the catalyst.

Original languageEnglish
Pages (from-to)8321-8323
Number of pages3
JournalJournal of the American Chemical Society
Issue number20
Publication statusPublished - 23 May 2012

ASJC Scopus subject areas

  • Catalysis
  • General Chemistry
  • Biochemistry
  • Colloid and Surface Chemistry


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