A systems biology approach to investigate the effect of pH-induced gene regulation on solvent production by Clostridium acetobutylicum in continuous culture

Sylvia Haus; Sara Jabbari; Thomas Millat; Holger Janssen; Ralf-Jörg Fischer; Hubert Bahl; John R King; Olaf Wolkenhauer

doi:10.1186/1752-0509-5-10

A systems biology approach to investigate the effect of pH-induced gene regulation on solvent production by Clostridium acetobutylicum in continuous culture

Sylvia Haus, Sara Jabbari, Thomas Millat, Holger Janssen, Ralf-Jörg Fischer, Hubert Bahl, John R King, Olaf Wolkenhauer

Mathematics

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Abstract

Clostridium acetobutylicum is an anaerobic bacterium which is known for its solvent-producing capabilities, namely regarding the bulk chemicals acetone and butanol, the latter being a highly efficient biofuel. For butanol production by C. acetobutylicum to be optimized and exploited on an industrial scale, the effect of pH-induced gene regulation on solvent production by C. acetobutylicum in continuous culture must be understood as fully as possible.

Original language	English
Pages (from-to)	10
Journal	BMC systems biology
Volume	5
DOIs	https://doi.org/10.1186/1752-0509-5-10
Publication status	Published - 2011

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abstract = "Clostridium acetobutylicum is an anaerobic bacterium which is known for its solvent-producing capabilities, namely regarding the bulk chemicals acetone and butanol, the latter being a highly efficient biofuel. For butanol production by C. acetobutylicum to be optimized and exploited on an industrial scale, the effect of pH-induced gene regulation on solvent production by C. acetobutylicum in continuous culture must be understood as fully as possible.",

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AU - Bahl, Hubert

AU - King, John R

AU - Wolkenhauer, Olaf

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A systems biology approach to investigate the effect of pH-induced gene regulation on solvent production by Clostridium acetobutylicum in continuous culture

Abstract

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