TY - JOUR
T1 - A study into the anti-microbial properties of an amino functionalised polymer using multi-parameter flow cytometry
AU - Hewitt, Christopher
AU - Franke, R
AU - Marx, A
AU - Kossmann, B
AU - Ottersbach, P
PY - 2004/1/1
Y1 - 2004/1/1
N2 - Fluorescent staining techniques were used to study the anti-microbial properties of aqueous suspensions of a novel, water insoluble amino functionalised polymer on three micro-organisms Pseudomonas fluorescens, Staphylococcus epidermidis and Saccharomyses cerevisiae. The mechanism of action was similar for each organism in that, after various contact times with the polymer, a progressive change in individual cell physiological state was measured using multi-parameter flow cytometry. The microbiocidal activity of this polymer may be similar to that of substances referred to as polycationic, amphipathic compounds ( peptides, peptide derivatives and other polyamines).
AB - Fluorescent staining techniques were used to study the anti-microbial properties of aqueous suspensions of a novel, water insoluble amino functionalised polymer on three micro-organisms Pseudomonas fluorescens, Staphylococcus epidermidis and Saccharomyses cerevisiae. The mechanism of action was similar for each organism in that, after various contact times with the polymer, a progressive change in individual cell physiological state was measured using multi-parameter flow cytometry. The microbiocidal activity of this polymer may be similar to that of substances referred to as polycationic, amphipathic compounds ( peptides, peptide derivatives and other polyamines).
KW - membranes
KW - anti-microbial polymers
KW - microbiocides
KW - flow cytometry
UR - http://www.scopus.com/inward/record.url?scp=1842760513&partnerID=8YFLogxK
U2 - 10.1023/B:BILE.0000021954.82099.a0
DO - 10.1023/B:BILE.0000021954.82099.a0
M3 - Article
C2 - 15168853
SN - 1573-6776
VL - 26
SP - 549
EP - 557
JO - Biotechnology Letters
JF - Biotechnology Letters
IS - 7
ER -