A Stimuli-Responsive Rotaxane-Gold Catalyst: Regulation of Activity and Diastereoselectivity

Marzia Galli; James E.M. Lewis; Stephen M. Goldup

doi:10.1002/anie.201505464

A Stimuli-Responsive Rotaxane-Gold Catalyst: Regulation of Activity and Diastereoselectivity

Marzia Galli, James E.M. Lewis, Stephen M. Goldup^*

^*Corresponding author for this work

Chemistry

Research output: Contribution to journal › Article › peer-review

107 Citations (Scopus)

Abstract

A rotaxane-based Au catalyst was developed and the effect of the mechanical bond on its behavior was studied. Unlike the non-interlocked thread, the rotaxane requires a catalytically innocent cofactor, the identity of which significantly influences both the yield and diastereoselectivity of the reaction. Under optimized conditions, Au^I (the catalyst), Ag^I (to abstract the Cl^- ligand), and Cu^I (the cofactor) combine to produce a catalyst with excellent activity and selectivity.

Original language	English
Pages (from-to)	13545-13549
Number of pages	5
Journal	Angewandte Chemie - International Edition
Volume	54
Issue number	46
DOIs	https://doi.org/10.1002/anie.201505464
Publication status	Published - 1 Nov 2015

Bibliographical note

Publisher Copyright:
© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Keywords

catalysts
gold
molecular machines
rotaxanes
supramolecular chemistry

ASJC Scopus subject areas

Catalysis
General Chemistry

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AU - Goldup, Stephen M.

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AB - A rotaxane-based Au catalyst was developed and the effect of the mechanical bond on its behavior was studied. Unlike the non-interlocked thread, the rotaxane requires a catalytically innocent cofactor, the identity of which significantly influences both the yield and diastereoselectivity of the reaction. Under optimized conditions, AuI (the catalyst), AgI (to abstract the Cl- ligand), and CuI (the cofactor) combine to produce a catalyst with excellent activity and selectivity.

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KW - gold

KW - molecular machines

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KW - supramolecular chemistry

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A Stimuli-Responsive Rotaxane-Gold Catalyst: Regulation of Activity and Diastereoselectivity

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

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