A Stimuli-Responsive Rotaxane-Gold Catalyst: Regulation of Activity and Diastereoselectivity

Marzia Galli, James E.M. Lewis, Stephen M. Goldup*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

107 Citations (Scopus)

Abstract

A rotaxane-based Au catalyst was developed and the effect of the mechanical bond on its behavior was studied. Unlike the non-interlocked thread, the rotaxane requires a catalytically innocent cofactor, the identity of which significantly influences both the yield and diastereoselectivity of the reaction. Under optimized conditions, AuI (the catalyst), AgI (to abstract the Cl- ligand), and CuI (the cofactor) combine to produce a catalyst with excellent activity and selectivity.

Original languageEnglish
Pages (from-to)13545-13549
Number of pages5
JournalAngewandte Chemie - International Edition
Volume54
Issue number46
DOIs
Publication statusPublished - 1 Nov 2015

Bibliographical note

Publisher Copyright:
© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Keywords

  • catalysts
  • gold
  • molecular machines
  • rotaxanes
  • supramolecular chemistry

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

Fingerprint

Dive into the research topics of 'A Stimuli-Responsive Rotaxane-Gold Catalyst: Regulation of Activity and Diastereoselectivity'. Together they form a unique fingerprint.

Cite this