A review of inherited platelet disorders with guidelines for their management on behalf of the UKHCDO

PHB Bolton-Maggs; EA Chalmers; PW Collins; P Harrison; S Kitchen; RJ Liesner; A Minford; AD Mumford; LA Parapia; DB Perry; Steve Watson; Johnathan Wilde; MD Williams

doi:10.1111/j.1365-2141.2006.06343.x

A review of inherited platelet disorders with guidelines for their management on behalf of the UKHCDO

PHB Bolton-Maggs, EA Chalmers, PW Collins, P Harrison, S Kitchen, RJ Liesner, A Minford, AD Mumford, LA Parapia, DB Perry, Steve Watson, Johnathan Wilde, MD Williams

Research output: Contribution to journal › Review article

258 Citations (Scopus)

Abstract

The inherited platelet disorders are an uncommon cause of symptomatic bleeding. They may be difficult to diagnose (and are likely to be under-diagnosed) and pose problems in management. This review discusses the inherited platelet disorders summarising the current state of the art with respect to investigation and diagnosis and suggests how to manage bleeding manifestations with particular attention to surgical interventions and the management of pregnancy.

Original language	English
Pages (from-to)	603-633
Number of pages	31
Journal	British Journal of Haematology
Volume	135
Issue number	5
DOIs	https://doi.org/10.1111/j.1365-2141.2006.06343.x
Publication status	Published - 1 Dec 2006

Keywords

inherited platelet disorders
thrombocytopenia
platelet bleeding
platelet glycoproteins
platelet receptors

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10.1111/j.1365-2141.2006.06343.x

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Bolton-Maggs, PHB., Chalmers, EA., Collins, PW., Harrison, P., Kitchen, S., Liesner, RJ., Minford, A., Mumford, AD., Parapia, LA., Perry, DB., Watson, S., Wilde, J., & Williams, MD. (2006). A review of inherited platelet disorders with guidelines for their management on behalf of the UKHCDO. British Journal of Haematology, 135(5), 603-633. https://doi.org/10.1111/j.1365-2141.2006.06343.x

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abstract = "The inherited platelet disorders are an uncommon cause of symptomatic bleeding. They may be difficult to diagnose (and are likely to be under-diagnosed) and pose problems in management. This review discusses the inherited platelet disorders summarising the current state of the art with respect to investigation and diagnosis and suggests how to manage bleeding manifestations with particular attention to surgical interventions and the management of pregnancy.",

keywords = "inherited platelet disorders, thrombocytopenia, platelet bleeding, platelet glycoproteins, platelet receptors",

author = "PHB Bolton-Maggs and EA Chalmers and PW Collins and P Harrison and S Kitchen and RJ Liesner and A Minford and AD Mumford and LA Parapia and DB Perry and Steve Watson and Johnathan Wilde and MD Williams",

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doi = "10.1111/j.1365-2141.2006.06343.x",

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Bolton-Maggs, PHB, Chalmers, EA, Collins, PW, Harrison, P, Kitchen, S, Liesner, RJ, Minford, A, Mumford, AD, Parapia, LA, Perry, DB, Watson, S, Wilde, J & Williams, MD 2006, 'A review of inherited platelet disorders with guidelines for their management on behalf of the UKHCDO', British Journal of Haematology, vol. 135, no. 5, pp. 603-633. https://doi.org/10.1111/j.1365-2141.2006.06343.x

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T1 - A review of inherited platelet disorders with guidelines for their management on behalf of the UKHCDO

AU - Bolton-Maggs, PHB

AU - Chalmers, EA

AU - Collins, PW

AU - Harrison, P

AU - Kitchen, S

AU - Liesner, RJ

AU - Minford, A

AU - Mumford, AD

AU - Parapia, LA

AU - Perry, DB

AU - Watson, Steve

AU - Wilde, Johnathan

AU - Williams, MD

PY - 2006/12/1

Y1 - 2006/12/1

N2 - The inherited platelet disorders are an uncommon cause of symptomatic bleeding. They may be difficult to diagnose (and are likely to be under-diagnosed) and pose problems in management. This review discusses the inherited platelet disorders summarising the current state of the art with respect to investigation and diagnosis and suggests how to manage bleeding manifestations with particular attention to surgical interventions and the management of pregnancy.

AB - The inherited platelet disorders are an uncommon cause of symptomatic bleeding. They may be difficult to diagnose (and are likely to be under-diagnosed) and pose problems in management. This review discusses the inherited platelet disorders summarising the current state of the art with respect to investigation and diagnosis and suggests how to manage bleeding manifestations with particular attention to surgical interventions and the management of pregnancy.

KW - inherited platelet disorders

KW - thrombocytopenia

KW - platelet bleeding

KW - platelet glycoproteins

KW - platelet receptors

U2 - 10.1111/j.1365-2141.2006.06343.x

DO - 10.1111/j.1365-2141.2006.06343.x

M3 - Review article

C2 - 17107346

SN - 1365-2141

VL - 135

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EP - 633

JO - British Journal of Haematology

JF - British Journal of Haematology

IS - 5

ER -

A review of inherited platelet disorders with guidelines for their management on behalf of the UKHCDO

Abstract

Keywords

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