A randomised phase III trial of the pharmacokinetic biomodulation of irinotecan using oral ciclosporin in advanced colorectal cancer: results of the Panitumumab, Irinotecan & Ciclosporin in COLOrectal cancer therapy trial (PICCOLO)

Gary Middleton, Sarah Brown, Catherine Lowe, Timothy Maughan, Stephen Gwyther, Alfred Oliver, Susan Richman, Denise Blake, Vicky Napp, Helen Marshall, Jonathan Wadsley, Nick Maisey, Ian Chau, Mark Hill, Simon Gollins, Sun Myint, Sarah Slater, John Wagstaff, John Bridgewater, Matthew Seymour

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