Abstract
The patterning of cells in insect segments requires the exchange of information between cells, which in Drosophila depends on the activity of members of the segment-polarity class of genes. Here we report the molecular characterization of one such gene, patched. We find that patched encodes a large protein with several possible membrane-spanning domains and is expressed in a complex pattern during embryogenesis.
Original language | English |
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Pages (from-to) | 508-13 |
Number of pages | 6 |
Journal | Nature |
Volume | 341 |
Issue number | 6242 |
DOIs | |
Publication status | Published - 12 Oct 1989 |
Keywords
- Alleles
- Amino Acid Sequence
- Animals
- Base Sequence
- Cloning, Molecular
- DNA
- Drosophila
- Embryo, Nonmammalian
- Genes
- Membrane Proteins
- Molecular Sequence Data
- Protein Conformation
- Restriction Mapping
- Journal Article
- Research Support, Non-U.S. Gov't