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Abstract
Proton beam therapy can potentially offer improved treatment for cancers of the head and neck and in paediatric patients. There has been a sharp uptake of proton beam therapy in recent years as improved delivery techniques and patient benefits are observed. However, treatments are currently planned using conventional x-ray CT images due to the absence of devices able to perform high quality proton computed tomography (pCT) under realistic clinical conditions. A new plastic-scintillator-based range telescope concept, named ASTRA, is proposed here to measure the proton's energy loss in a pCT system. Simulations conducted using GEANT4 yield an expected energy resolution of 0.7%. If calorimetric information is used the energy resolution could be further improved to about 0.5%. In addition, the ability of ASTRA to track multiple protons simultaneously is presented. Due to its fast components, ASTRA is expected to reach unprecedented data collection rates, similar to 108 protons/s. The performance of ASTRA has also been tested by simulating the imaging of phantoms. The results show excellent image contrast and relative stopping power reconstruction.
Original language | English |
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Article number | 035013 |
Number of pages | 14 |
Journal | Physics in Medicine and Biology |
Volume | 67 |
Issue number | 3 |
Early online date | 3 Feb 2022 |
DOIs | |
Publication status | Published - 7 Feb 2022 |
Bibliographical note
Publisher Copyright:© 2022 Institute of Physics and Engineering in Medicine.
Keywords
- CT scan
- Monte Carlo simulation
- proton CT
- proton therapy
- range telescope
- tracking
ASJC Scopus subject areas
- Radiological and Ultrasound Technology
- Radiology Nuclear Medicine and imaging
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OPTIMA: Optimising proton therapy through imaging
Allport, P. (Researcher) & Price, T. (Principal Investigator)
Engineering & Physical Science Research Council
1/05/18 → 31/05/25
Project: Research Councils