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A novel framework to assess the prevention value of a health intervention

  • Jonathan Pearson-Stuttard*
  • , Catrin Treharne
  • , Robert King
  • , Hugo Harper
  • , Irina Pokhilenko
  • , Manuel Gomes
  • , Louis Garrison
  • , Ricardo Reynoso
  • , Jutta Kloppenborg Heick Skau
  • , Katherine Byrne
  • *Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

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Abstract

Aims: Interest in capturing chronic disease prevention impacts on broader economic and societal outcomes is growing; however, this has been challenging to date. We present a comprehensive framework to support assessment of prevention value from a range of stakeholder perspectives, using obesity as an illustrative example.

Materials and Methods: We identified three domains in which to group value components: individual health/health system, societal, and government. Longlisting and shortlisting of value components was supported by a targeted literature review, quality assessment against four criteria and review by six health economic and policy experts. Worked examples illustrate the applicability of the framework using two UK-based hypothetical intervention effects: a 5% obesity incidence reduction and a 0.5-unit improvement in SF-12 scores.

Results: Twenty-nine value components were identified: 7 related to individual health/healthcare system, 18 to societal and 4 to government value. Of these, 17 were shortlisted into 9 categories: individual health, healthcare system, productivity, family impact, health equity and social mobility, environmental, income-related benefits, sickness benefits, and income tax. We also identified six components for future consideration, where current data and methodologies are limited.

Conclusions: We propose a value framework that goes beyond traditional health benefit measures to holistically assess chronic disease prevention value. While data limitations prevented the quantification of all shortlisted components, this does not preclude a qualitative discussion of these components in evaluating a preventative intervention. The framework should now be tested with live interventions and key stakeholders to standardise methodologies and enhance future acceptability and use.
Original languageEnglish
JournalDiabetes, Obesity and Metabolism
Early online date5 Nov 2025
DOIs
Publication statusE-pub ahead of print - 5 Nov 2025

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • obesity prevention
  • societal value
  • value assessment

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