A mechanical basis for chromosome function

N Kleckner, D Zickler, Gareth Jones, J Dekker, R Padmore, J Henle, J Hutchinson

Research output: Contribution to journalArticle

211 Citations (Scopus)


We propose that chromosome function is governed by internal mechanical forces generated by programmed tendencies for expansion of the DNA/chromatin fiber against constraining features.
Original languageEnglish
Pages (from-to)12592-12597
Number of pages6
JournalNational Academy of Sciences. Proceedings
Early online date16 Aug 2004
Publication statusPublished - 16 Aug 2004


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