A mechanical basis for chromosome function

N Kleckner; D Zickler; Gareth Jones; J Dekker; R Padmore; J Henle; J Hutchinson

doi:10.1073/pnas.0402724101

A mechanical basis for chromosome function

N Kleckner, D Zickler, Gareth Jones, J Dekker, R Padmore, J Henle, J Hutchinson

Biosciences

Research output: Contribution to journal › Article

211 Citations (Scopus)

Abstract

We propose that chromosome function is governed by internal mechanical forces generated by programmed tendencies for expansion of the DNA/chromatin fiber against constraining features.

Original language	English
Pages (from-to)	12592-12597
Number of pages	6
Journal	National Academy of Sciences. Proceedings
Volume	101
Early online date	16 Aug 2004
DOIs	https://doi.org/10.1073/pnas.0402724101
Publication status	Published - 16 Aug 2004

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abstract = "We propose that chromosome function is governed by internal mechanical forces generated by programmed tendencies for expansion of the DNA/chromatin fiber against constraining features.",

author = "N Kleckner and D Zickler and Gareth Jones and J Dekker and R Padmore and J Henle and J Hutchinson",

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AU - Zickler, D

AU - Jones, Gareth

AU - Dekker, J

AU - Padmore, R

AU - Henle, J

AU - Hutchinson, J

PY - 2004/8/16

Y1 - 2004/8/16

N2 - We propose that chromosome function is governed by internal mechanical forces generated by programmed tendencies for expansion of the DNA/chromatin fiber against constraining features.

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SP - 12592

EP - 12597

JO - National Academy of Sciences. Proceedings

JF - National Academy of Sciences. Proceedings

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A mechanical basis for chromosome function

Abstract

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