TY - JOUR
T1 - A late Neolithic expansion of y chromosomal haplogroup O2a1-M95 from east to west
AU - The Genographic Consortium
AU - Arunkumar, Ganeshprasad
AU - Wei, Lan Hai
AU - Kavitha, Valampuri John
AU - Syama, Adhikarla
AU - Arun, Varatharajan Santhakumari
AU - Sathua, Surendra
AU - Sahoo, Raghunath
AU - Balakrishnan, R.
AU - Riba, Tomo
AU - Chakravarthy, Jharna
AU - Chaudhury, Bapukan
AU - Panda, Premanada
AU - Das, Pradipta K.
AU - Nayak, Prasanna K.
AU - Li, Hui
AU - Pitchappan, Ramasamy
AU - Adlera, Christina J.
AU - Balanovska, Elena
AU - Balanovsky, Oleg
AU - Bertranpetit, Jaume
AU - Clarke, Andrew C.
AU - Comas, David
AU - Cooper, Alan
AU - Der Sarkissian, Clio S.I.
AU - Dulik, Matthew C.
AU - Gaieski, Jill B.
AU - Haak, Wolfgang
AU - Haber, Marc
AU - Hobbs, Angela
AU - Javed, Asif
AU - Jin, Li
AU - Kaplan, Matthew E.
AU - Li, Shilin
AU - Martínez-Cruz, Begoña
AU - Matisoo-Smith, Elizabeth A.
AU - Melé, Marta
AU - Merchant, Nirav C.
AU - Mitchell, R. John
AU - Owings, Amanda C.
AU - Parida, Laxmi
AU - Platt, Daniel E.
AU - Quintana-Murci, Lluis
AU - Renfrew, Colin
AU - Lacerda, Daniela R.
AU - Royyuru, Ajay K.
AU - Schurr, Theodore G.
AU - Santos, Fabrício R.
AU - Soodyall, Himla
AU - Hernanz, David F.Soria
AU - Swamikrishnan, Pandikumar
N1 - Publisher Copyright:
© 2015 Institute of Botany, Chinese Academy of Sciences.
PY - 2015/11
Y1 - 2015/11
N2 - The origin and dispersal of Y-Chromosomal haplogroup O2a1-M95, distributed across the Austro Asiatic speaking belt of East and South Asia, are yet to be fully understood. Various studies have suggested either an East Indian or Southeast Asian origin of O2a1-M95. We addressed the issue of antiquity and dispersal of O2a1-M95 by sampling 8748 men from India, Laos, and China and compared them to 3307 samples from other intervening regions taken from the literature. Analyses of haplogroup frequency and Y-STR data on a total 2413 O2a1-M95 chromosomes revealed that the Laos samples possessed the highest frequencies of O2a1-M95 (74% with >0.5) and its ancestral haplogroups (O2-P31, O-M175) as well as a higher proportion of samples with 14STR-median haplotype (17 samples in 14 populations), deep coalescence time (5.7-±-0.3 Kya) and consorted O2a1-M95 expansion evidenced from STR evolution. All these suggested Laos to carry a deep antiquity of O2a1-M95 among the study regions. A serial decrease in expansion time from east to west: 5.7-±-0.3 Kya in Laos, 5.2-±-0.6 in Northeast India, and 4.3-±-0.2 in East India, suggested a late Neolithic east to west spread of the lineage O2a1-M95 from Laos.
AB - The origin and dispersal of Y-Chromosomal haplogroup O2a1-M95, distributed across the Austro Asiatic speaking belt of East and South Asia, are yet to be fully understood. Various studies have suggested either an East Indian or Southeast Asian origin of O2a1-M95. We addressed the issue of antiquity and dispersal of O2a1-M95 by sampling 8748 men from India, Laos, and China and compared them to 3307 samples from other intervening regions taken from the literature. Analyses of haplogroup frequency and Y-STR data on a total 2413 O2a1-M95 chromosomes revealed that the Laos samples possessed the highest frequencies of O2a1-M95 (74% with >0.5) and its ancestral haplogroups (O2-P31, O-M175) as well as a higher proportion of samples with 14STR-median haplotype (17 samples in 14 populations), deep coalescence time (5.7-±-0.3 Kya) and consorted O2a1-M95 expansion evidenced from STR evolution. All these suggested Laos to carry a deep antiquity of O2a1-M95 among the study regions. A serial decrease in expansion time from east to west: 5.7-±-0.3 Kya in Laos, 5.2-±-0.6 in Northeast India, and 4.3-±-0.2 in East India, suggested a late Neolithic east to west spread of the lineage O2a1-M95 from Laos.
KW - Laos
KW - migration
KW - Neolithic
KW - NRY
KW - O2a1-M95
UR - https://www.scopus.com/pages/publications/84945257110
U2 - 10.1111/jse.12147
DO - 10.1111/jse.12147
M3 - Article
AN - SCOPUS:84945257110
SN - 1674-4918
VL - 53
SP - 546
EP - 560
JO - Journal of Systematics and Evolution
JF - Journal of Systematics and Evolution
IS - 6
ER -