A dynamic CD2-rich compartment at the outer edge of the immunological synapse boosts and integrates signals

Philippos Demetriou; Enas Abu-Shah; Salvatore Valvo; Sarah McCuaig; Viveka Mayya; Audun Kvalvaag; Thomas Starkey; Kseniya Korobchevskaya; Lennard Y. W. Lee; Matthias Friedrich; Elizabeth Mann; Mikhail A. Kutuzov; Matteo Morotti; Nina Wietek; Heather Rada; Shamsideen Yusuf; Jehan Afrose; Anastasios Siokis; Philip Allan; Timothy Ambrose; Carolina Arancibia; Adam Bailey; Ellie Barnes; Elizabeth Bird-Lieberman; Jan Bornschein; Oliver Brain; Barbara Braden; Jane Collier; Jeremy Cobbold; Emma Culver; James East; Lucy Howarth; Paul Klenerman; Simon Leedham; Rebecca Palmer; Michael Pavlides; Fiona Powrie; Astor Rodrigues; Jack Satsangi; Alison Simmons; Peter Sullivan; Holm Uhlig; Alissa Walsh; Michael Meyer-Hermann; Ahmed Ashour Ahmed; David Depoil; Michael L. Dustin

doi:10.1038/s41590-020-0770-x

A dynamic CD2-rich compartment at the outer edge of the immunological synapse boosts and integrates signals

Philippos Demetriou
, Enas Abu-Shah
, Salvatore Valvo
, Sarah McCuaig
, Viveka Mayya
, Audun Kvalvaag
, Thomas Starkey
, Kseniya Korobchevskaya
, Lennard Y. W. Lee
, Matthias Friedrich
, Elizabeth Mann
, Mikhail A. Kutuzov
, Matteo Morotti
, Nina Wietek
, Heather Rada
, Shamsideen Yusuf
, Jehan Afrose
, Anastasios Siokis
, Philip Allan
, Timothy Ambrose

Carolina Arancibia, Adam Bailey, Ellie Barnes, Elizabeth Bird-Lieberman, Jan Bornschein, Oliver Brain, Barbara Braden, Jane Collier, Jeremy Cobbold, Emma Culver, James East, Lucy Howarth, Paul Klenerman, Simon Leedham, Rebecca Palmer, Michael Pavlides, Fiona Powrie, Astor Rodrigues, Jack Satsangi, Alison Simmons, Peter Sullivan, Holm Uhlig, Alissa Walsh, Michael Meyer-Hermann, Ahmed Ashour Ahmed, David Depoil, Michael L. Dustin

Cancer and Genomic Sciences

Research output: Contribution to journal › Article › peer-review

Original language	English
Journal	Nature Immunology
DOIs	https://doi.org/10.1038/s41590-020-0770-x
Publication status	Published - 14 Oct 2020

Access to Document

10.1038/s41590-020-0770-x

Cite this

Demetriou, P., Abu-Shah, E., Valvo, S., McCuaig, S., Mayya, V., Kvalvaag, A., Starkey, T., Korobchevskaya, K., Lee, L. Y. W., Friedrich, M., Mann, E., Kutuzov, M. A., Morotti, M., Wietek, N., Rada, H., Yusuf, S., Afrose, J., Siokis, A., Allan, P., ... Dustin, M. L. (2020). A dynamic CD2-rich compartment at the outer edge of the immunological synapse boosts and integrates signals. Nature Immunology. https://doi.org/10.1038/s41590-020-0770-x

@article{86086177f75a40aba91789d4097c02cc,

title = "A dynamic CD2-rich compartment at the outer edge of the immunological synapse boosts and integrates signals",

author = "Philippos Demetriou and Enas Abu-Shah and Salvatore Valvo and Sarah McCuaig and Viveka Mayya and Audun Kvalvaag and Thomas Starkey and Kseniya Korobchevskaya and Lee, \{Lennard Y. W.\} and Matthias Friedrich and Elizabeth Mann and Kutuzov, \{Mikhail A.\} and Matteo Morotti and Nina Wietek and Heather Rada and Shamsideen Yusuf and Jehan Afrose and Anastasios Siokis and Philip Allan and Timothy Ambrose and Carolina Arancibia and Adam Bailey and Ellie Barnes and Elizabeth Bird-Lieberman and Jan Bornschein and Oliver Brain and Barbara Braden and Jane Collier and Jeremy Cobbold and Emma Culver and James East and Lucy Howarth and Paul Klenerman and Simon Leedham and Rebecca Palmer and Michael Pavlides and Fiona Powrie and Astor Rodrigues and Jack Satsangi and Alison Simmons and Peter Sullivan and Holm Uhlig and Alissa Walsh and Michael Meyer-Hermann and Ahmed, \{Ahmed Ashour\} and David Depoil and Dustin, \{Michael L.\}",

year = "2020",

month = oct,

day = "14",

doi = "10.1038/s41590-020-0770-x",

language = "English",

journal = "Nature Immunology",

issn = "1529-2908",

publisher = "Nature Publishing Group",

}

Demetriou, P, Abu-Shah, E, Valvo, S, McCuaig, S, Mayya, V, Kvalvaag, A, Starkey, T, Korobchevskaya, K, Lee, LYW, Friedrich, M, Mann, E, Kutuzov, MA, Morotti, M, Wietek, N, Rada, H, Yusuf, S, Afrose, J, Siokis, A, Allan, P, Ambrose, T, Arancibia, C, Bailey, A, Barnes, E, Bird-Lieberman, E, Bornschein, J, Brain, O, Braden, B, Collier, J, Cobbold, J, Culver, E, East, J, Howarth, L, Klenerman, P, Leedham, S, Palmer, R, Pavlides, M, Powrie, F, Rodrigues, A, Satsangi, J, Simmons, A, Sullivan, P, Uhlig, H, Walsh, A, Meyer-Hermann, M, Ahmed, AA, Depoil, D & Dustin, ML 2020, 'A dynamic CD2-rich compartment at the outer edge of the immunological synapse boosts and integrates signals', Nature Immunology. https://doi.org/10.1038/s41590-020-0770-x

TY - JOUR

T1 - A dynamic CD2-rich compartment at the outer edge of the immunological synapse boosts and integrates signals

AU - Demetriou, Philippos

AU - Abu-Shah, Enas

AU - Valvo, Salvatore

AU - McCuaig, Sarah

AU - Mayya, Viveka

AU - Kvalvaag, Audun

AU - Starkey, Thomas

AU - Korobchevskaya, Kseniya

AU - Lee, Lennard Y. W.

AU - Friedrich, Matthias

AU - Mann, Elizabeth

AU - Kutuzov, Mikhail A.

AU - Morotti, Matteo

AU - Wietek, Nina

AU - Rada, Heather

AU - Yusuf, Shamsideen

AU - Afrose, Jehan

AU - Siokis, Anastasios

AU - Allan, Philip

AU - Ambrose, Timothy

AU - Arancibia, Carolina

AU - Bailey, Adam

AU - Barnes, Ellie

AU - Bird-Lieberman, Elizabeth

AU - Bornschein, Jan

AU - Brain, Oliver

AU - Braden, Barbara

AU - Collier, Jane

AU - Cobbold, Jeremy

AU - Culver, Emma

AU - East, James

AU - Howarth, Lucy

AU - Klenerman, Paul

AU - Leedham, Simon

AU - Palmer, Rebecca

AU - Pavlides, Michael

AU - Powrie, Fiona

AU - Rodrigues, Astor

AU - Satsangi, Jack

AU - Simmons, Alison

AU - Sullivan, Peter

AU - Uhlig, Holm

AU - Walsh, Alissa

AU - Meyer-Hermann, Michael

AU - Ahmed, Ahmed Ashour

AU - Depoil, David

AU - Dustin, Michael L.

PY - 2020/10/14

Y1 - 2020/10/14

UR - https://doi.org/10.1038/s41590-020-0770-x

U2 - 10.1038/s41590-020-0770-x

DO - 10.1038/s41590-020-0770-x

M3 - Article

SN - 1529-2908

JO - Nature Immunology

JF - Nature Immunology

ER -