A critique of functional localisers

KJ Friston, Pia Rotshtein, JJ Geng, P Sterzer, RN Henson

Research output: Contribution to journalArticle

274 Citations (Scopus)

Abstract

In this critique, we review the usefulness of functional localising scans in functional MRI studies. We consider their conceptual motivations and the implications for experimental design and inference. Functional localisers can often be viewed as acquiring data from cells that have been removed from an implicit factorial design. This perspective reveals their potentially restrictive nature. We deconstruct two examples from the recent literature to highlight the key issues. We conclude that localiser scans can be unnecessary and, in some instances, lead to a biased and inappropriately constrained characterisation of functional anatomy.
Original languageEnglish
Pages (from-to)1077-1087
Number of pages11
JournalNeuroImage
Volume30
Issue number4
DOIs
Publication statusPublished - 1 May 2006

Fingerprint

Dive into the research topics of 'A critique of functional localisers'. Together they form a unique fingerprint.

Cite this