TY - JOUR
T1 - A case-control study of elderly patients with acute respiratory illness: effect of influenza vaccination on admission to hospital in winter 2003-2004
AU - Jordan, Rachel
AU - Hawker, JI
AU - Ayres, Jonathan
AU - Tunnicliffe, W
AU - Adab, Peymane
AU - Olowokure, Babatunde
AU - Kai, J
AU - McManus, Richard
AU - Salter, Rosaleen
AU - Cheng, Kar
PY - 2007/11/14
Y1 - 2007/11/14
N2 - Every winter, hospitals face a large increase in emergency respiratory admissions in elderly people. A case-control study was undertaken to assess the effect of routine influenza vaccine in preventing such admissions among a cohort of UK elderly presenting with acute respiratory illness during winter 2003-2004. 157 hospitalised cases and 639 controls (matched for age, sex and week of consultation) were interviewed. In a winter typical of levels of circulating influenza in recent years, influenza vaccine did not show a protective effect on emergency respiratory admissions overall (adjusted OR 1.2 (95%CI 0.8, 1.9). Policy makers should not rely solely on influenza vaccine routinely having a large effect on winter pressures, and should focus on additional preventive strategies.
AB - Every winter, hospitals face a large increase in emergency respiratory admissions in elderly people. A case-control study was undertaken to assess the effect of routine influenza vaccine in preventing such admissions among a cohort of UK elderly presenting with acute respiratory illness during winter 2003-2004. 157 hospitalised cases and 639 controls (matched for age, sex and week of consultation) were interviewed. In a winter typical of levels of circulating influenza in recent years, influenza vaccine did not show a protective effect on emergency respiratory admissions overall (adjusted OR 1.2 (95%CI 0.8, 1.9). Policy makers should not rely solely on influenza vaccine routinely having a large effect on winter pressures, and should focus on additional preventive strategies.
U2 - 10.1016/j.vaccine.2007.09.005
DO - 10.1016/j.vaccine.2007.09.005
M3 - Article
C2 - 17935837
VL - 25
SP - 7909
EP - 7913
JO - Vaccine
JF - Vaccine
IS - 46
ER -