A boronic acid-based fluorescent hydrogel for monosaccharide detection

Suying Xu, Adam Sedgwick, Souad Elfeky, Wenbo Chen, Ashley Jones, George Williams, Toby Jenkins, Steven Bull, John Fossey, Tony James

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)
177 Downloads (Pure)

Abstract

A boronic acid-based anthracene fluorescent probe was functionalised with an acrylamide unit to incorporate into a hydrogel system for monosaccharide detection. In solution, the fluorescent probe displayed a strong fluorescence turn-on response upon exposure to fructose, and an expected trend in apparent binding constants, as judged by a fluorescence response where d–fructose > d–galactose > d–mannose > d–glucose. The hydrogel incorporating the boronic acid monomer demonstrated the ability to detect monosaccharides by fluorescence with the same overall trend as the monomer in solution with the addition of d–fructose resulting in a 10-fold enhancement (≼0.25 mol/L).
Original languageEnglish
Pages (from-to)112-116
JournalFrontiers of Chemical Science and Engineering
Volume2020
DOIs
Publication statusPublished - 21 May 2019

ASJC Scopus subject areas

  • Chemical Engineering(all)

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