A bioartificial liver - State of the art

Alastair Strain, James Neuberger

Research output: Contribution to journalArticle

271 Citations (Scopus)


End-stage liver disease is treated by liver transplantation, but donor organ shortages remain a serious problem. This has prompted the design of bioartificial liver devices to "bridge" patients until they either recover or receive a liver transplant. In these devices, patient plasma is circulated extracorporeally through a bioreactor that houses liver cells (hepatocytes) sandwiched between artificial plates or capillaries.
Original languageEnglish
Pages (from-to)1005-1009
Number of pages5
Issue number5557
Publication statusPublished - 1 Feb 2002


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