Abstract
End-stage liver disease is treated by liver transplantation, but donor organ shortages remain a serious problem. This has prompted the design of bioartificial liver devices to "bridge" patients until they either recover or receive a liver transplant. In these devices, patient plasma is circulated extracorporeally through a bioreactor that houses liver cells (hepatocytes) sandwiched between artificial plates or capillaries.
| Original language | English |
|---|---|
| Pages (from-to) | 1005-1009 |
| Number of pages | 5 |
| Journal | Science |
| Volume | 295 |
| Issue number | 5557 |
| DOIs | |
| Publication status | Published - 1 Feb 2002 |