3-({5-Bromo-4-[pyrrolidin-1-yl]pyrimidin-2-yl}amino)phenol

Alan Jones

doi:10.3390/M859

3-({5-Bromo-4-[pyrrolidin-1-yl]pyrimidin-2-yl}amino)phenol

Alan Jones

Pharmacy

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Abstract

Re-investigation of the ¹H-NMR spectrum reported for 1⁵-bromo-4-oxa-2,9-diaza-1(2,4)-pyrimidine-3(1,3)-benzenacyclononaphane (2) prepared via a Mitsunobu- mediated macroether cyclisation led to a proposed structural isomer (3). The title compound (3) was prepared via a two-step protocol and assigned using ¹H, ¹³C-NMR and LC-MS.

Original language	English
Article number	M859
Number of pages	4
Journal	MolBank
Volume	2015
Issue number	2
DOIs	https://doi.org/10.3390/M859
Publication status	Published - 21 May 2015

Keywords

macrocyclic ether
Mitsunobu
macrocyclisation

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title = "3-({5-Bromo-4-[pyrrolidin-1-yl]pyrimidin-2-yl}amino)phenol",

abstract = "Re-investigation of the 1H-NMR spectrum reported for 15-bromo-4-oxa-2,9-diaza-1(2,4)-pyrimidine-3(1,3)-benzenacyclononaphane (2) prepared via a Mitsunobu- mediated macroether cyclisation led to a proposed structural isomer (3). The title compound (3) was prepared via a two-step protocol and assigned using 1H, 13C-NMR and LC-MS.",

keywords = "macrocyclic ether, Mitsunobu, macrocyclisation",

author = "Alan Jones",

year = "2015",

month = may,

day = "21",

doi = "10.3390/M859",

language = "English",

volume = "2015",

journal = "MolBank",

issn = "1422-8599",

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TY - JOUR

T1 - 3-({5-Bromo-4-[pyrrolidin-1-yl]pyrimidin-2-yl}amino)phenol

AU - Jones, Alan

PY - 2015/5/21

Y1 - 2015/5/21

N2 - Re-investigation of the 1H-NMR spectrum reported for 15-bromo-4-oxa-2,9-diaza-1(2,4)-pyrimidine-3(1,3)-benzenacyclononaphane (2) prepared via a Mitsunobu- mediated macroether cyclisation led to a proposed structural isomer (3). The title compound (3) was prepared via a two-step protocol and assigned using 1H, 13C-NMR and LC-MS.

AB - Re-investigation of the 1H-NMR spectrum reported for 15-bromo-4-oxa-2,9-diaza-1(2,4)-pyrimidine-3(1,3)-benzenacyclononaphane (2) prepared via a Mitsunobu- mediated macroether cyclisation led to a proposed structural isomer (3). The title compound (3) was prepared via a two-step protocol and assigned using 1H, 13C-NMR and LC-MS.

KW - macrocyclic ether

KW - Mitsunobu

KW - macrocyclisation

U2 - 10.3390/M859

DO - 10.3390/M859

M3 - Article

SN - 1422-8599

VL - 2015

JO - MolBank

JF - MolBank

IS - 2

M1 - M859

ER -

3-({5-Bromo-4-[pyrrolidin-1-yl]pyrimidin-2-yl}amino)phenol

Abstract

Keywords

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