2,7-Diazabicyclo[2.2.1]heptanes: novel asymmetric access and controlled bridge-opening

Gary Peczkowski, Philip Craven, Darren Stead, Nigel Simpkins

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)
114 Downloads (Pure)

Abstract

Organocatalysed asymmetric Michael additions of substituted triketopiperazines to enones afford products in high yield and enantiomeric ratio (er). Further modification delivers products possessing natural product (NP) scaffolds including diazabicyclo[2.2.1]heptane, prolinamide and harmicine.
Original languageEnglish
Pages (from-to)4214-4217
Number of pages4
JournalChemical Communications
Volume55
Issue number29
DOIs
Publication statusPublished - 12 Mar 2019

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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