Vaccine immunity in patients with chronic lymphocytic leukaemia; mechanisms of response and optimisation strategies for patients on targeted therapies

Parry, Helen (Principal Investigator)

Immunology and Immunotherapy

Short title	Vaccine immunity in patients with chronic lymphocytic leukaemia; mechanisms of response and optimisation strategies for patients on targeted therapies
Status	Active
Effective start/end date	1/04/23 → 31/03/28

Funding

Medical Research Council

3 Article

Robust Adaptive Immunity to MPXV in Older People Who Received Childhood Vaccinia Vaccination
Davis, C., Zuo, J., Bruton, R., Hodges, M., Roberts, T., Manali, M., Olmo, P., Willett, B., Moss, P. & Parry, H., 26 Jan 2026, In: Biology. 15, 3, 11 p., 234.
Research output: Contribution to journal › Article › peer-review

Open Access
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16 Downloads (Pure)
A 3-week pause versus continued Bruton tyrosine kinase inhibitor use during COVID-19 vaccination in individuals with chronic lymphocytic leukaemia (IMPROVE trial): a randomised, open-label, superiority trial
Cook, J. A., Patten, P. E. M., Peckham, N., Moss, P., Phillips, N., Abhishek, A., Roberts, T., Hodges, M., Talbot, G., Barber, V., Francis, A., Shields, A. M., Duley, L., Hoogeboom, R., Willett, B. J., Scott, S., Parry-Jones, N., Eyre, T. A., Plested, G. & Vandici, G. & 8 others, Wandroo, F. A., Hutchinson, C., Paneesha, S., Murray, D. J., Martinez-Calle, N., Jenkins, S., Heartin, E. & Parry, H. M., Apr 2025, In: The Lancet Haematology. 12, 4, p. e294-e303 10 p.
Research output: Contribution to journal › Article › peer-review

Open Access
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67 Downloads (Pure)
TCF1 and LEF1 promote B-1a cell homeostasis and regulatory function
Shen, Q., Wang, H., Roco, J. A., Meng, X., Bosticardo, M., Hodges, M., Battaglia, M., Feng, Z. P., Talks, B. J., Powell, J., Shanmugiah, V. B. M., Chu, J., Rahman, N. M., Elsheikh, A., Chakravarty, P., Grenov, A., Emmerich, M., Delmonte, O. M., Freeman, A. F. & Keller, M. D. & 14 others, Belaid, B., Papa, I., Lee, J. C., Cañete, P. F., Gonzalez-Figueroa, P., Zhang, Y., Xue, H. H., Turajlic, S., Notarangelo, L. D., Haniffa, M., Garrett-Sinha, L. A., Parry, H. M., Kanellakis, N. I. & Vinuesa, C. G., 9 Oct 2025, In: Nature. 646, 8084, p. 442-451 10 p.
Research output: Contribution to journal › Article › peer-review

Open Access
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130 Downloads (Pure)

Vaccine immunity in patients with chronic lymphocytic leukaemia; mechanisms of response and optimisation strategies for patients on targeted therapies

Project Details

Funding

Fingerprint

Robust Adaptive Immunity to MPXV in Older People Who Received Childhood Vaccinia Vaccination

A 3-week pause versus continued Bruton tyrosine kinase inhibitor use during COVID-19 vaccination in individuals with chronic lymphocytic leukaemia (IMPROVE trial): a randomised, open-label, superiority trial

TCF1 and LEF1 promote B-1a cell homeostasis and regulatory function

Vaccine immunity in patients with chronic lymphocytic leukaemia; mechanisms of response and optimisation strategies for patients on targeted therapies

Project Details

Funding

Fingerprint

Research output

Robust Adaptive Immunity to MPXV in Older People Who Received Childhood Vaccinia Vaccination

A 3-week pause versus continued Bruton tyrosine kinase inhibitor use during COVID-19 vaccination in individuals with chronic lymphocytic leukaemia (IMPROVE trial): a randomised, open-label, superiority trial

TCF1 and LEF1 promote B-1a cell homeostasis and regulatory function