Understanding the rewiring of growth signalling in FLT3-ITD and RAS mutant leukaemias after treatment with FLT3 and RAS inhibitors

Coleman, Daniel (Principal Investigator)

Cancer and Genomic Sciences

Short title	Understanding the rewiring of growth signalling in FLT3-ITD and RAS mutant leukaemias after treatment with FLT3 and RAS inhibitors
Status	Finished
Effective start/end date	1/12/22 → 29/02/24

Funding

The Royal Society

1 Article

Pharmacological inhibition of RAS overcomes FLT3 inhibitor resistance in FLT3-ITD+ AML through AP-1 and RUNX1
Coleman, D. J. L., Keane, P., Chin, P. S., Ames, L., Kellaway, S., Blair, H., Khan, N., Griffin, J., Holmes, E., Maytum, A., Potluri, S., Strate, L., Koscielniak, K., Raghavan, M., Bushweller, J., Heidenreich, O., Rabbitts, T., Cockerill, P. N. & Bonifer, C., 19 Apr 2024, In: iScience. 27, 4, 109576.
Research output: Contribution to journal › Article › peer-review

Open Access
File
109 Downloads (Pure)