Understanding the mechanism by which tetraspanins regulate the 'molecular scissor' ADAM10

Dafforn, Tim (Co-Investigator)
Tomlinson, Michael (Principal Investigator)
Gough, Rich (Co-Investigator)

Biosciences

Short title	Understanding the mechanism by which tetraspanins regulate the 'molecular scissor' ADAM10
Status	Finished
Effective start/end date	1/07/17 → 30/06/20

Funding

Biotechnology & Biological Sciences Research Council

Purification and characterisation of the platelet-activating GPVI/FcRγ complex in SMALPs
Wang, X., Slater, A., Lee, S. C., Harrison, N., Pollock, N. L., Bakker, S. E., Navarro, S., Nieswandt, B., Dafforn, T. R., García, Á., Watson, S. P. & Tomlinson, M. G., Apr 2024, In: Archives of Biochemistry and Biophysics. 754, 13 p., 109944.
Research output: Contribution to journal › Article › peer-review

Open Access
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The Platelet Collagen Receptor GPVI Is Cleaved by Tspan15/ADAM10 and Tspan33/ADAM10 Molecular Scissors
Koo, C. Z., Matthews, A. L., Harrison, N., Szyroka, J., Nieswandt, B., Gardiner, E., Poulter, N. S. & Tomlinson, M. G., 23 Feb 2022, In: International Journal of Molecular Sciences. 23, 5, 2440.
Research output: Contribution to journal › Article › peer-review

Open Access
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105 Downloads (Pure)
Regulation of ADAM10 by the TspanC8 Family of Tetraspanins and Their Therapeutic Potential
Harrison, N., Koo, C. Z. & Tomlinson, M. G., 23 Jun 2021, In: International Journal of Molecular Sciences. 22, 13, 16 p., 6707.
Research output: Contribution to journal › Review article › peer-review

Open Access
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142 Downloads (Pure)