Toxic DNA: A Model for All Domains of Life

Grainger, David (Principal Investigator)

Biosciences

Short title	Toxic DNA: A Model for All Domains of Life
Status	Finished
Effective start/end date	1/02/19 → 31/07/25

Funding

The Wellcome Trust

Activation of bacterial transcription by distortion of promoter base pairing
Klimova, K. M., Forrest, D., Sharma, P., Haycocks, J. R. J. & Grainger, D. C., 13 Jan 2026, In: Nucleic Acids Research. 54, 1, 14 p., gkaf1424.
Research output: Contribution to journal › Article › peer-review

Open Access
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Bidirectional promoters in Escherichia coli: regulatory rules and implications for gene expression noise
Warman, E. A., Forrest, D., Stringer, A. M., Wade, J. T. & Grainger, D. C., 10 Feb 2026, In: Nucleic Acids Research. 54, 3, 12 p., gkag028.
Research output: Contribution to journal › Article › peer-review

Open Access
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3 Downloads (Pure)
The bacterial RNA polymerase-associated CarD protein couples promoter activity to DNA supercoiling
Forrest, D., Warman, E. A. & Grainger, D. C., 10 Mar 2026, In: Nature Communications. 17, 1, 16 p., 2295.
Research output: Contribution to journal › Article › peer-review

Open Access
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8 Downloads (Pure)