The Use Of Novel Polymer-Lipid Nanoparticles To Study G-Protein-Coupled Receptor Activation And Dynamics.

Wheatley, Mark (Principal Investigator)
Dafforn, Tim (Co-Investigator)

Biosciences

Short title	The Use Of Novel Polymer-Lipid Nanoparticles To Study G-Protein-Coupled Receptor Activation And Dynamics.
Status	Finished
Effective start/end date	1/01/12 → 31/12/14

Funding

Biotechnology & Biological Sciences Research Council

7 Article

A method for detergent-free isolation of membrane protein with its local lipid environment
Lee, S. C., Knowles, T. J., Postis, V. L. G., Jamshad, M., Parslow, R. A., Lin, Y.-P., Goldman, A., Sridhar, P., Overduin, M., Muench, S. P. & Dafforn, T. R., 1 Jul 2016, In: Nature protocols. 11, 7, p. 1149–1162 14 p.
Research output: Contribution to journal › Article › peer-review

Open Access
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175 Citations (Scopus)

985 Downloads (Pure)
GPCR-styrene maleic acid lipid particles (GPCR-SMALPs): their nature and potential
Wheatley, M., Charlton, J., Jamshad, M., Routledge, S. J., Bailey, S., La-Borde, P. J., Azam, M. T., Logan, R. T., Bill, R. M., Dafforn, T. & Poyner, D. R., 11 Apr 2016, In: Biochemical Society Transactions. 44, 2, p. 619-623 5 p.
Research output: Contribution to journal › Article › peer-review

Open Access
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21 Citations (Scopus)

555 Downloads (Pure)
Membrane protein extraction and purification using styrene–maleic acid (SMA) copolymer: effect of variations in polymer structure
Morrison, K., Akram, A., Mathews, A., Khan, Z., Patel, J., Zhou, C., Hardy, D., Moore-Kelly, C., Patel, R., Obida, V., Knowles, T., Javed, M.-U.-H., Chmel, N., Dafforn, T. & Rothnie, A., 25 Nov 2016, In: Biochemical Journal. 473, 23, p. 4349-4360
Research output: Contribution to journal › Article › peer-review

Open Access
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60 Citations (Scopus)

1465 Downloads (Pure)