The Use Of Novel Polymer-Lipid Nanoparticles To Study G-Protein-Coupled Receptor Activation And Dynamics.

Wheatley, Mark (Principal Investigator)
Dafforn, Tim (Co-Investigator)

Biosciences

Short title	The Use Of Novel Polymer-Lipid Nanoparticles To Study G-Protein-Coupled Receptor Activation And Dynamics.
Status	Finished
Effective start/end date	1/01/12 → 31/12/14

Funding

Biotechnology & Biological Sciences Research Council

7 Article

A method for detergent-free isolation of membrane protein with its local lipid environment
Lee, S. C., Knowles, T. J., Postis, V. L. G., Jamshad, M., Parslow, R. A., Lin, Y., Goldman, A., Sridhar, P., Overduin, M., Muench, S. P. & Dafforn, T. R., 1 Jul 2016, In: Nature protocols. 11, 7, p. 1149–1162 14 p.
Research output: Contribution to journal › Article › peer-review

Open Access
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175 Citations (Scopus)

604 Downloads (Pure)
GPCR-styrene maleic acid lipid particles (GPCR-SMALPs): their nature and potential
Wheatley, M., Charlton, J., Jamshad, M., Routledge, S. J., Bailey, S., La-Borde, P. J., Azam, M. T., Logan, R. T., Bill, R. M., Dafforn, T. & Poyner, D. R., 11 Apr 2016, In: Biochemical Society Transactions. 44, 2, p. 619-623 5 p.
Research output: Contribution to journal › Article › peer-review

Open Access
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21 Citations (Scopus)

365 Downloads (Pure)
Membrane protein extraction and purification using styrene–maleic acid (SMA) copolymer: effect of variations in polymer structure
Morrison, K., Akram, A., Mathews, A., Khan, Z., Patel, J., Zhou, C., Hardy, D., Moore-Kelly, C., Patel, R., Obida, V., Knowles, T., Javed, M., Chmel, N., Dafforn, T. & Rothnie, A., 25 Nov 2016, In: Biochemical Journal. 473, 23, p. 4349-4360
Research output: Contribution to journal › Article › peer-review

Open Access
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60 Citations (Scopus)

980 Downloads (Pure)