Project Details
| Short title | The second extracellular loop of the CGRP receptor: A docking site for vasoprotective ligands |
|---|---|
| Status | Finished |
| Effective start/end date | 1/01/14 → 31/12/16 |
Funding
- British Heart Foundation
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Research output
- 6 Article
-
Receptor activity-modifying protein dependent and independent activation mechanisms in the coupling of calcitonin gene-related peptide and adrenomedullin receptors to Gs
Woolley, M. J., Reynolds, C. A., Simms, J., Walker, C. S., Mobarec, J. C., Garelja, M. L., Conner, A. C., Poyner, D. R. & Hay, D. L., 11 Jul 2017, (E-pub ahead of print) In: Biochemical Pharmacology.Research output: Contribution to journal › Article › peer-review
Open Access15 Citations (Scopus) -
Relative Antagonism of Mutants of the CGRP Receptor Extracellular Loop 2 Domain (ECL2) Using a Truncated Competitive Antagonist (CGRP8-37): Evidence for the Dual Involvement of ECL2 in the Two-Domain Binding Model
Woolley, M. J., Simms, J., Uddin, S., Poyner, D. R. & Conner, A. C., 1 Aug 2017, In: Biochemistry. 56, 30, p. 3877-3880 4 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)226 Downloads (Pure) -
Understanding the molecular functions of the second extracellular loop (ECL2) of the calcitonin gene-related peptide (CGRP) receptor using a comprehensive mutagenesis approach
Woolley, M., Simms, J., Mobarec, J. C., Reynolds, C. A., Poyner, D. R. & Conner, A., 30 May 2017, (E-pub ahead of print) In: Molecular and Cellular Endocrinology.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)219 Downloads (Pure)