The role of RUNX1 and the AP-1 transcription factor family in t(8;21) AML

Cockerill, Peter (Co-Investigator)
Bonifer, Conny (Principal Investigator)

Cancer and Genomic Sciences

Short title	The role of RUNX1 and the AP-1 transcription factor family in t(8;21) AML
Status	Finished
Effective start/end date	1/10/20 → 31/12/23

Funding

BLOODWISE

3 Article
1 Letter

Fusion gene depletion eliminates stemness and induces bidirectional differentiation of acute myeloid leukemia
Derevyanko, P. K., Swart, L. E., Mata Casimiro, L. D., van Oort, A., du Plessis, M., van den Brink, L., Ashtiani, M., Zwaan, C. M., Krippner-Heidenreich, A., Bonifer, C., Schiffelers, R., Vormoor, J., Kellaway, S. G. & Heidenreich, O., 11 Dec 2025, In: Blood. 146, 24, p. 2963-2978 16 p.
Research output: Contribution to journal › Article › peer-review

Open Access
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Gene regulation in t(6;9) DEK::NUP214 Acute Myeloid Leukemia resembles that of FLT3-ITD/NPM1 Acute Myeloid Leukemia but with an altered HOX/MEIS axis
Potluri, S., Kellaway, S. G., Coleman, D. J. L., Keane, P., Imperato, M. R., Assi, S. A., Cockerill, P. N. & Bonifer, C., Feb 2024, In: Leukemia. 38, 2, p. 403-407 5 p.
Research output: Contribution to journal › Letter › peer-review

Open Access
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114 Downloads (Pure)
Leukemic stem cells activate lineage inappropriate signalling pathways to promote their growth
Kellaway, S. G., Potluri, S., Keane, P., Blair, H. J., Ames, L., Worker, A., Chin, P. S., Ptasinska, A., Derevyanko, P. K., Adamo, A., Coleman, D. J. L., Khan, N., Assi, S. A., Krippner-Heidenreich, A., Raghavan, M., Cockerill, P. N., Heidenreich, O. & Bonifer, C., 14 Feb 2024, In: Nature Communications. 15, 1, 22 p., 1359.
Research output: Contribution to journal › Article › peer-review

Open Access
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254 Downloads (Pure)